Evidence map›Paper›PMID 37446060›Full record

ArticleInternational journal of molecular sciences2023

Data Normalization of Urine miRNA Profiling from Head and Neck Cancer Patients Treated with Cisplatin.

Nadine de Godoy Torso, Julia Coelho França Quintanilha, Maria Aparecida Cursino, Eder de Carvalho Pincinato, Carmen Silvia Passos Lima, Patricia Moriel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nadine de Godoy TorsoSchool of Medical Sciences, University of Campinas, Campinas 13083894, Brazil.ORCID 0000-0002-9692-6099
Julia Coelho França QuintanilhaSchool of Medical Sciences, University of Campinas, Campinas 13083894, Brazil.ORCID 0000-0001-6908-4474
Maria Aparecida CursinoSchool of Medical Sciences, University of Campinas, Campinas 13083894, Brazil.
Eder de Carvalho PincinatoSchool of Medical Sciences, University of Campinas, Campinas 13083894, Brazil.
Carmen Silvia Passos LimaSchool of Medical Sciences, University of Campinas, Campinas 13083894, Brazil.
Patricia MorielFaculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083970, Brazil.ORCID 0000-0002-4927-7022
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001São Paulo Research Foundation 2017/02338-0 and 2019/20010-7
6 · The paper itself

Abstract

The microRNA (miRNA) expression profile by qRT-PCR depends directly on the most appropriate normalization strategy adopted; however, currently there is no universally adequate reference gene. Therefore, this study aimed to determine, considering RNA-Seq results, the most adequate endogenous normalizer for use in the relative quantification of urine miRNAs from head and neck cancer patients, treated with cisplatin chemoradiotherapy. The massive sequencing was performed to identify the miRNAs differentially expressed between the group with cisplatin nephrotoxicity (

Indexed as

Head and Neck NeoplasmsMicroRNAsCisplatinGene Expression ProfilingGermanyHumansCisplatinMicroRNAsMIRN363 microRNA, humanMIRN-875 microRNA, humancisplatinendogenous normalizermicroRNAqRT-PCRreference gene

Identifiers

PMID37446060
PMCPMC10341608
OpenAlexW4382790198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.