Evidence map›Paper›PMID 37446057›Full record

ReviewInternational journal of molecular sciences2023

Microfluidics and Organoids, the Power Couple of Developmental Biology and Oncology Studies.

Laura Ann Hetzel, Ahmed Ali, Vincenzo Corbo, Thomas Hankemeier

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Advancing organ-on-chip systems: the role of microfluidics in neuro-cardiac research.Current research in pharmacology and drug discovery · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura Ann HetzelLeiden Academic Center for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.ORCID 0000-0002-6922-9423
Ahmed AliLeiden Academic Center for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.ORCID 0000-0003-2157-4399
Vincenzo CorboDepartment of Diagnostics and Public Health, ARC-Net Research Centre, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-6340-8009
Thomas HankemeierLeiden Academic Center for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.ORCID 0000-0001-7871-2073

Funding

Marie Skłodowska-Curie Actions EU (MSCA-ITN 861196, PRECODE
6 · The paper itself

Abstract

Organoids are an advanced cell model that hold the key to unlocking a deeper understanding of in vivo cellular processes. This model can be used in understanding organ development, disease progression, and treatment efficacy. As the scientific world embraces the model, it must also establish the best practices for cultivating organoids and utilizing them to the greatest potential in assays. Microfluidic devices are emerging as a solution to overcome the challenges of organoids and adapt assays. Unfortunately, the various applications of organoids often depend on specific features in a device. In this review, we discuss the options and considerations for features and materials depending on the application and development of the organoid.

Indexed as

MicrofluidicsOrganoidsDevelopmental BiologyLab-On-A-Chip DevicesMedical Oncologymicrofluidic deviceorganoid filteringorganoid formationorganoids

Identifiers

PMID37446057
PMCPMC10341942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.