Evidence map›Paper›PMID 37446025›Full record

ArticleInternational journal of molecular sciences2023

Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers.

Spencer R Rosario, Bowen Dong, Yali Zhang, Hua-Hsin Hsiao, Emily Isenhart, Jianmin Wang, Erin M Siegel, Arta M Monjazeb, Dwight H Owen, Prasenjit Dey and 13 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Germline whole-exome sequencing revealsJournal for immunotherapy of cancer · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 1 country.

Spencer R RosarioDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.ORCID 0000-0002-2626-9257
Bowen DongDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Yali ZhangDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Hua-Hsin HsiaoDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Emily IsenhartDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Jianmin WangDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Erin M SiegelDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0003-1779-2510
Arta M MonjazebDepartment of Radiation Oncology, University of California Davis, Sacramento, CA 95616, USA.
Dwight H OwenDepartment of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.
Prasenjit DeyDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Fred K TabungDepartment of Epidemiology, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.ORCID 0000-0001-8193-7150
Daniel J SpakowiczDepartment of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.ORCID 0000-0003-2314-6435
William J MurphyDepartment of Immunology, University of California Davis, Sacramento, CA 95616, USA.
Stephen EdgeDepartment of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Sai YendamuriDepartment of Thoracic Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Sami IbrahimiDepartment of Medicine, Oklahoma University Health Stephenson Cancer Center, Oklahoma City, OK 73104, USA.
Jill M KolesarDepartment of Pharmacy, University of Kentucky College of Pharmacy, Lexington, KY 40506, USA.ORCID 0000-0003-1802-6439
Patsy H McDonaldDepartment of Cancer Biology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Deepak VadehraDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Michelle ChurchmanPrecision Therapy and Diagnostics, Aster Insights, Hudson, FL 34667, USA.
Song LiuDepartment of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Pawel KalinskiDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Sarbajit MukherjeeDepartment of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Roswell Park Comprehensive Cancer Center · USThe Ohio State University · USMoffitt Cancer Center · USUniversity of California, Davis · USOU HealthUniversity of Kentucky · US

Funding

The Impact of Obesity on Radiotherapy Anti-Tumor EffectsR01CA240751 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Arta Monir Monjazeb · 2022 to 2026
$2.9M
NCI NIH HHS R01 CA240751
6 · The paper itself

Abstract

The prevalence of obesity, defined as the body mass index (BMI) ≥ 30 kg/m

Indexed as

AdenocarcinomaGastrointestinal NeoplasmsFemaleHumansKynurenineLeukocytes, MononuclearMaleObesityTryptophanKynurenineTryptophancancergender disparityimmunitymetabolismobesityomics

Identifiers

PMID37446025
PMCPMC10342094
OpenAlexW4382786438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.