ReviewInternational journal of molecular sciences2023
Nicotianamine: A Key Player in Metal Homeostasis and Hyperaccumulation in Plants.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Analysis of the TaNAS gene family in bread wheat identifies additional members and candidates for intragenic biofortification.Journal of experimental botany · 2026Article
- Review
- PGPR-induced regulation of Zn and Fe transporters in wheat (Triticum aestivum L.) uncovered through integrated genome-wide analysis and functional validation.BMC plant biology · 2026Article
- Nickel Toxicity in Plants.International journal of molecular sciences · 2026Review
- Seed Nanopriming with Spirulina-Derived Carbon Dots Enhances Rice (Plants (Basel, Switzerland) · 2026Article
- Expanding Iron Acquisition in Maize: Root Sector-Specific Responses and Gibberellin Regulation of Ferric and Ferrous Iron Uptake.International journal of molecular sciences · 2026Article
- Identification of the Nicotianamine synthase (NAS) gene family in wheat (Triticum aestivum L.) and the role of its member TaNAS4-A in Zn and Fe transport.Functional & integrative genomics · 2025Article
- Biofortification of Durum Wheat Grain: Interactions Between Micronutrients as Affected by Potential Biofortification Enhancers and Surfactants.Plants (Basel, Switzerland) · 2025Article
- Transcriptomic and physiological analyses revealed nicotianamine enhances wheat tolerance to excess manganese.iScience · 2025Article
- Zinc translocation from Zn-sufficient to Zn-deficient roots as an adaptation to heterogeneous Zn availability.BMC plant biology · 2025Article
- Toward Nutrient-Rich Rice: Biofortification through Mineral Accumulation and Low Phytic Acid Content.Journal of agricultural and food chemistry · 2025Article
- Engineering of nicotianamine synthesis enhances cadmium mobility in plants and results in higher seed cadmium concentrations.The Plant journal : for cell and molecular biology · 2025Article
- Identification and characterization of QTL for grain protein content derived from the D genome of allohexaploid wheat.Frontiers in plant science · 2025Article
- Improving NiInternational journal of molecular sciences · 2024Article
- The Role of Low-Molecular-Weight Organic Acids in Metal Homeostasis in Plants.International journal of molecular sciences · 2024Review
- Coordination chemistry suggests that independently observed benefits of metformin and ZnBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- Flavonoid metabolism plays an important role in response to lead stress in maize at seedling stage.BMC plant biology · 2024Article
- Physiological and Transcriptomic Analyses Reveal Commonalities and Specificities in Wheat in Response to Aluminum and Manganese.Current issues in molecular biology · 2024Article
- Changes in folic acid, phenolic components, and angiotensin-converting enzyme inhibitory activity in cowpea (Science progressArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Nicotianamine (NA) is a low-molecular-weight N-containing metal-binding ligand, whose accumulation in plant organs changes under metal deficiency or excess. Although NA biosynthesis can be induced in vivo by various metals, this non-proteinogenic amino acid is mainly involved in the detoxification and transport of iron, zinc, nickel, copper and manganese. This review summarizes the current knowledge on NA biosynthesis and its regulation, considers the mechanisms of NA secretion by plant roots, as well as the mechanisms of intracellular transport of NA and its complexes with metals, and its role in radial and long-distance metal transport. Its role in metal tolerance is also discussed. The NA contents in excluders, storing metals primarily in roots, and in hyperaccumulators, accumulating metals mainly in shoots, are compared. The available data suggest that NA plays an important role in maintaining metal homeostasis and hyperaccumulation mechanisms. The study of metal-binding compounds is of interdisciplinary significance, not only regarding their effects on metal toxicity in plants, but also in connection with the development of biofortification approaches to increase the metal contents, primarily of iron and zinc, in agricultural plants, since the deficiency of these elements in food crops seriously affects human health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.