Evidence map›Paper›PMID 37445982›Full record

ArticleInternational journal of molecular sciences2023

Accelerated Bone Loss in Transgenic Mice Expressing Constitutively Active TGF-β Receptor Type I.

Parichart Toejing, Nithidol Sakunrangsit, Pinyada Pho-On, Chinnatam Phetkong, Asada Leelahavanichkul, Somyoth Sridurongrit, Matthew B Greenblatt, Sutada Lotinun

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Advances in Bone Biology.International journal of molecular sciences · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Parichart ToejingCenter of Excellence in Skeletal Disorders and Enzyme Reaction Mechanism, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
Nithidol SakunrangsitCenter of Excellence in Skeletal Disorders and Enzyme Reaction Mechanism, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-1759-5974
Pinyada Pho-OnCenter of Excellence in Skeletal Disorders and Enzyme Reaction Mechanism, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
Chinnatam PhetkongCenter of Excellence in Skeletal Disorders and Enzyme Reaction Mechanism, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-9721-8342
Asada LeelahavanichkulDivision of Immunology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Somyoth SridurongritDepartment of Anatomy, Faculty of Science, Mahidol University, Bangkok 10330, Thailand.
Matthew B GreenblattDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine and Research Division, Hospital for Special Surgery, New York, NY 10065, USA.
Sutada LotinunCenter of Excellence in Skeletal Disorders and Enzyme Reaction Mechanism, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-5127-3039
Chulalongkorn University · THHospital for Special Surgery · USMahidol University · TH

Funding

Faculty Research Grant (DRF66004), Faculty of Dentistry, Thailand Science research and Innova-tion Fund (CU_FRB65_hea (5)_011_32_06), and the Second Century Fund (C2F), Chulalongkorn University. DRF66004 andCU_FRB65_hea (5)_011_32_06
6 · The paper itself

Abstract

Transforming growth factor beta (TGF-β) is a key factor mediating the intercellular crosstalk between the hematopoietic stem cells and their microenvironment. Here, we investigated the skeletal phenotype of transgenic mice expressing constitutively active TGF-β receptor type I under the control of Mx1-Cre (

Indexed as

Bone Diseases, MetabolicCore Binding Factor Alpha 1 SubunitAnimalsCell DifferentiationHedgehog ProteinsMiceMice, TransgenicOsteoblastsOsteoclastsReceptors, Transforming Growth Factor betaCore Binding Factor Alpha 1 SubunitHedgehog ProteinsReceptors, Transforming Growth Factor betabonehardnessosteoblastosteoclastTGF-β

Identifiers

PMID37445982
PMCPMC10341885
OpenAlexW4382724667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.