Evidence map›Paper›PMID 37445965›Full record

ArticleInternational journal of molecular sciences2023

Exploring the Therapeutic Potential of

Tatiana Takahasi Komoto, Felipe Garcia Nishimura, Adriane Feijó Evangelista, Ana Julia Aguiar de Freitas, Gabriel da Silva, Wilson Araujo Silva, Kamila Peronni, Marcia Maria Chiquitelli Marques, Mozart Marins, Ana Lucia Fachin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Synthesis, andCurrent computer-aided drug design · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Tatiana Takahasi KomotoBiotechnology Unit, University of Ribeirão Preto, SP, Av. Costábile Romano, 2201, Ribeirão Preto 14096-900, Brazil.ORCID 0000-0001-5287-0866
Felipe Garcia NishimuraBiotechnology Unit, University of Ribeirão Preto, SP, Av. Costábile Romano, 2201, Ribeirão Preto 14096-900, Brazil.ORCID 0000-0001-7177-0043
Adriane Feijó EvangelistaSergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Manguinhos, Rio de Janeiro 21040-361, Brazil.ORCID 0000-0002-4731-2082
Ana Julia Aguiar de FreitasMolecular Oncology Research Center, Barretos Cancer Hospital, Teaching and Research Institute, Barretos 14784-400, Brazil.ORCID 0000-0002-9677-2093
Gabriel da SilvaBiotechnology Unit, University of Ribeirão Preto, SP, Av. Costábile Romano, 2201, Ribeirão Preto 14096-900, Brazil.ORCID 0000-0002-5660-9769
Wilson Araujo SilvaCenter for Medical Genomics at the Clinics Hospital of Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, Brazil.ORCID 0000-0001-9364-2886
Kamila PeronniCenter for Medical Genomics at the Clinics Hospital of Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, Brazil.ORCID 0000-0002-8747-9282
Marcia Maria Chiquitelli MarquesMolecular Oncology Research Center, Barretos Cancer Hospital, Teaching and Research Institute, Barretos 14784-400, Brazil.ORCID 0000-0001-5616-6710
Mozart MarinsBiotechnology Unit, University of Ribeirão Preto, SP, Av. Costábile Romano, 2201, Ribeirão Preto 14096-900, Brazil.ORCID 0000-0001-7389-4023
Ana Lucia FachinBiotechnology Unit, University of Ribeirão Preto, SP, Av. Costábile Romano, 2201, Ribeirão Preto 14096-900, Brazil.ORCID 0000-0001-8755-9250
Universidade de Ribeirão Preto · BRHospital de Câncer de Barretos · BRUniversidade de São Paulo · BREscola Nacional de Saúde Pública · BR

Funding

São Paulo Research Foundation FAPESP 2019/10514-8
6 · The paper itself

Abstract

Breast cancer is responsible for 25% of all cancers that affect women. Due to its high heterogeneity pattern in clinical diagnosis and its molecular profile differences, researchers have been seeking new targets and therapies, with more specificity and fewer side effects. Thus, one compound that has garnered our attention is

Indexed as

Breast NeoplasmsChalconesMicroRNAsFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsChalconesMicroRNAsantitumorbreast cancerflavonoidmicroRNAtrans-chalcone

Identifiers

PMID37445965
PMCPMC10341840
OpenAlexW4382724648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.