Evidence map›Paper›PMID 37445839›Full record

ArticleInternational journal of molecular sciences2023

PER2 Promotes Odontoblastic/Osteogenic Differentiation of Dental Pulp Stem Cells by Modulating Mitochondrial Metabolism.

Wushuang Huang, Qi Huang, Hongwen He, Fang Huang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wushuang HuangHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Qi HuangHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Hongwen HeHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Fang HuangHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0003-3408-8090
Sun Yat-sen University · CN

Funding

National Natural Science Foundation of China No. 81870737Natural Science Foundation of Guangdong Province No. 2021A1515011779
6 · The paper itself

Abstract

Human dental pulp stem cells (hDPSCs) possess remarkable self-renewal and multilineage differentiation ability. PER2, an essential circadian molecule, regulates various physiological processes. Evidence suggests that circadian rhythm and PER2 participate in physiological functions of DPSCs. However, the influence of PER2 on DPSCs' differentiation remains largely unknown. This study aimed to explore the effect and potential mechanism of PER2 on hDPSCs' differentiation. Dental pulp tissues were extracted, and hDPSCs were cultured for

Indexed as

Dental PulpOsteogenesisAnimalsCell DifferentiationCell ProliferationCells, CulturedHumansMaleMiceOdontoblastsPeriod Circadian ProteinsStem CellsPER2 protein, humanPeriod Circadian Proteinsdental pulp stem cellsmitochondrial metabolismodontoblastic/osteogenic differentiationPER2

Identifiers

PMID37445839
PMCPMC10341716
OpenAlexW4382462170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.