Evidence map›Paper›PMID 37445821›Full record

ArticleInternational journal of molecular sciences2023

Small RNA Profiling in an HTLV-1-Infected Patient with Acute Adult T-Cell Leukemia-Lymphoma at Diagnosis and after Maintenance Therapy: A Case Study.

Rodrigo Pessôa, Daniela Raguer Valadão de Souza, Youko Nukui, Juliana Pereira, Lorena Abreu Fernandes, Rosa Nascimento Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb, Alberto José da Silva Duarte, Sabri Saeed Sanabani

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rodrigo PessôaPostgraduate Program in Translational Medicine, Department of Medicine, Federal University of São Paulo (UNIFESP), São Paulo 04039-002, Brazil.
Daniela Raguer Valadão de SouzaPostgraduate Program in Translational Medicine, Department of Medicine, Federal University of São Paulo (UNIFESP), São Paulo 04039-002, Brazil.
Youko NukuiDepartment of Hematology, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil.
Juliana PereiraDepartment of Hematology, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil.
Lorena Abreu FernandesPostgraduate Program in Translational Medicine, Department of Medicine, Federal University of São Paulo (UNIFESP), São Paulo 04039-002, Brazil.ORCID 0000-0002-8246-3126
Rosa Nascimento MarcussoDepartment of Neurology, Emilio Ribas Institute of Infectious Diseases, São Paulo 01246-900, Brazil.ORCID 0000-0002-8396-0263
Augusto César Penalva de OliveiraDepartment of Neurology, Emilio Ribas Institute of Infectious Diseases, São Paulo 01246-900, Brazil.ORCID 0000-0002-4084-7973
Jorge CassebLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0002-4553-2559
Alberto José da Silva DuarteLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo 05403-000, Brazil.
Sabri Saeed SanabaniLaboratory of Medical Investigation LIM-56, Division of Dermatology, Medical School, University of São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0002-8876-8262
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BRInstituto de Infectologia Emílio Ribas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small RNAs (sRNAs) are epigenetic regulators of essential biological processes associated with the development and progression of leukemias, including adult T-cell leukemia/lymphoma (ATLL) caused by human T-cell lymphotropic virus type 1 (HTLV-1), an oncogenic human retrovirus originally discovered in a patient with adult T-cell leukemia/lymphoma. Here, we describe the sRNA profile of a 30-year-old woman with ATLL at the time of diagnosis and after maintenance therapy with the aim of correlating expression levels with response to therapy.

Indexed as

Human T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellLymphomaAdultFemaleHumansRNARNAATLLHTLV-1massive parallel sequencingsmall RNA

Identifiers

PMID37445821
PMCPMC10342019
OpenAlexW4382137327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.