Evidence map›Paper›PMID 37445810›Full record

ArticleInternational journal of molecular sciences2023

ECM Composition Differentially Regulates Intracellular and Extracellular pH in Normal and Cancer Pancreatic Duct Epithelial Cells.

Daria Di Molfetta, Stefania Cannone, Maria Raffaella Greco, Rosa Caroppo, Francesca Piccapane, Tiago Miguel Amaral Carvalho, Concetta Altamura, Ilaria Saltarella, Diana Tavares Valente, Jean Francois Desaphy and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Daria Di MolfettaDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.
Stefania CannoneDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.
Maria Raffaella GrecoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.
Rosa CaroppoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.
Francesca PiccapaneDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.
Tiago Miguel Amaral CarvalhoDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0001-9095-1413
Concetta AltamuraDepartment of Biomedical Sciences and Human Oncology, School of Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0001-7306-9621
Ilaria SaltarellaDepartment of Biomedical Sciences and Human Oncology, School of Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.
Diana Tavares ValenteLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Jean Francois DesaphyDepartment of Biomedical Sciences and Human Oncology, School of Medicine, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0001-8816-9369
Stephan J ReshkinDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0001-9757-5908
Rosa Angela CardoneDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0002-2011-9135
University of Bari Aldo Moro · ITUniversity of Minho · PT

Funding

Marie Curie 813834; H2020-446 MSCA-ITN-2018
6 · The paper itself

Abstract

Intracellular pH (pHi) regulation is a challenge for the exocrine pancreas, where the luminal secretion of bicarbonate-rich fluid is accompanied by interstitial flows of acid. This acid-base transport requires a plethora of ion transporters, including bicarbonate transporters and the Na

Indexed as

AcidosisNeoplasmsBicarbonatesCollagen Type IEpithelial CellsExtracellular MatrixHumansHydrogen-Ion ConcentrationPancreatic DuctsSodium-Hydrogen ExchangersBicarbonatesCollagen Type ISodium-Hydrogen Exchangersbicarbonate transportNHE1PDAC

Identifiers

PMID37445810
PMCPMC10341693
OpenAlexW4382137964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.