Evidence map›Paper›PMID 37445740›Full record

ArticleInternational journal of molecular sciences2023

Inhibition of Pertussis Toxin by Human α-Defensins-1 and -5: Differential Mechanisms of Action.

Carolin Kling, Anja Sommer, Yasser Almeida-Hernandez, Armando Rodríguez, Julio A Perez-Erviti, Rajendra Bhadane, Ludger Ständker, Sebastian Wiese, Holger Barth, Mario Pupo-Meriño and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
  5. Effects of Bile on PathogenicBiomolecules · 2025
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Carolin KlingInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University Medical Center, 89081 Ulm, Germany.
Anja SommerInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University Medical Center, 89081 Ulm, Germany.
Yasser Almeida-HernandezComputational Bioengineering, Fakultät Bio- und Chemieingenieurwesen, Technische Universität Dortmund, 44227 Dortmund, Germany.ORCID 0000-0001-9832-3534
Armando RodríguezCore Facility Functional Peptidomics, Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Julio A Perez-ErvitiComputational Bioengineering, Fakultät Bio- und Chemieingenieurwesen, Technische Universität Dortmund, 44227 Dortmund, Germany.ORCID 0000-0003-2635-8767
Rajendra BhadaneInstitute of Biomedicine, University of Turku, FI-20520 Turku, Finland.ORCID 0000-0002-7330-4801
Ludger StändkerCore Facility Functional Peptidomics, Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Sebastian WieseCore Unit Mass Spectrometry and Proteomics, Faculty of Medicine, Ulm University, 89081 Ulm, Germany.
Holger BarthInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University Medical Center, 89081 Ulm, Germany.
Mario Pupo-MeriñoDepartamento de Bioinformática, Centro de Matemática Computacional, Universidad de las Ciencias Informáticas (UCI), Havana 19370, Cuba.ORCID 0000-0001-9130-0620
Arto T PulliainenInstitute of Biomedicine, University of Turku, FI-20520 Turku, Finland.
Elsa Sánchez-GarcíaComputational Bioengineering, Fakultät Bio- und Chemieingenieurwesen, Technische Universität Dortmund, 44227 Dortmund, Germany.
Katharina ErnstInstitute of Experimental and Clinical Pharmacology, Toxicology and Pharmacology of Natural Products, Ulm University Medical Center, 89081 Ulm, Germany.
Universität Ulm · DETU Dortmund University · DEUniversity of Turku · FIUniversity of Information Science · CU

Funding

Deutsche Forschungsgemeinschaft 316249678-SFB1279Deutsche Forschungsgemeinschaft 436586093Deutsche Forschungsgemeinschaft EXC 2033 - 390677874 - RESOLVGerman Academic Exchange Service 57592717-GLACIER
6 · The paper itself

Abstract

Whooping cough is a severe childhood disease, caused by the bacterium

Indexed as

Whooping CoughBordetella pertussisCell LineChildHumansPertussis ToxinProteinsPertussis ToxinProteinsantimicrobial peptidebacterial AB-type toxindefensinshuman peptidemechanism of inhibitionpertussis toxintoxin inhibitor

Identifiers

PMID37445740
PMCPMC10341622
OpenAlexW4382068895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.