Evidence map›Paper›PMID 37445551›Full record

ReviewJournal of clinical medicine2023

Personality Traits and Fatigue in Multiple Sclerosis: A Narrative Review.

Alessia Ciancio, Maria Claudia Moretti, Antimo Natale, Alessandro Rodolico, Maria Salvina Signorelli, Antonino Petralia, Mario Altamura, Antonello Bellomo, Aurora Zanghì, Emanuele D'Amico and 2 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Linking Personality Traits to Disability Progression in Multiple Sclerosis: A Longitudinal Analysis.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alessia CiancioDepartment of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-2327-7080
Maria Claudia MorettiDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Antimo NataleDepartment of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, 95123 Catania, Italy.
Alessandro RodolicoDepartment of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-2196-0601
Maria Salvina SignorelliDepartment of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-6941-9454
Antonino PetraliaDepartment of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, 95123 Catania, Italy.
Mario AltamuraDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Antonello BellomoDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Aurora ZanghìDepartment of Medical and Surgical Specialities, University of Foggia, 71122 Foggia, Italy.
Emanuele D'AmicoDepartment of Medical and Surgical Specialities, University of Foggia, 71122 Foggia, Italy.
Carlo AvolioDepartment of Medical and Surgical Specialities, University of Foggia, 71122 Foggia, Italy.
Carmen ConcertoDepartment of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-7426-5250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease. Fatigue is a prevalent and debilitating symptom that significantly impacts the quality of life of these patients. A relationship between personality traits and fatigue in MS has been hypothesized but not clearly defined. (2) Methods: A literature search was carried out from databases up to April 2023 for studies correlating personality traits and fatigue in patients suffering from MS. (3) Results: A total of ten articles was included; most of the studies depict a neuroticism-fatigue correlation; however, they were not consistent in terms of the fatigue, personality, and covariate assessments. (4) Conclusions: The clinical and methodological heterogeneity of the included studies prevented us from drawing any firm conclusion on the link between personality traits and fatigue in MS. Several models of personality and different fatigue assessments have been found. Despite this, a common pathway shows that the neuroticism trait or similar personality patterns has a role in fatigue diagnosis. This may be a useful target to improve the quality of life and enhance the modification of the disease treatment results. Further homogeneous and longitudinal studies are needed.

Indexed as

big five factorfatiguemultiple sclerosisneurodegenerative diseasepersonality traits

Identifiers

PMID37445551
PMCPMC10342558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.