Evidence map›Paper›PMID 37445521›Full record

ArticleJournal of clinical medicine2023

Time-Dependent Changes of Klotho and FGF-23 Levels after Kidney Transplantation: Role of Cold Ischemia Time, Renal Function and Graft Inflammation.

Teresa Vazquez-Sanchez, Maria Dolores Sanchez-Niño, Pedro Ruiz-Esteban, Veronica López, Myriam León, Abelardo Caballero, Juan Francisco Ruiz-Escalera, Alberto Ortiz, Armando Torres, Mariano Rodriguez and 1 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Teresa Vazquez-SanchezNephrology Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Malaga, Spain.
Maria Dolores Sanchez-NiñoPharmacology Department, IIS-Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, RICORS2040 (RD21/0005/0001), E-28040 Madrid, Spain.ORCID 0000-0001-7110-6409
Pedro Ruiz-EstebanNephrology Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Malaga, Spain.
Veronica LópezNephrology Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Malaga, Spain.
Myriam LeónPathology Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Málaga, Spain.ORCID 0000-0002-5547-5842
Abelardo CaballeroImmunology Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Malaga, Spain.
Juan Francisco Ruiz-EscaleraClinical Analysis Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Malaga, Spain.ORCID 0000-0002-3641-0963
Alberto OrtizNephrology Department, IIS-Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, RICORS2040 (RD21/0005/0001), E-28040 Madrid, Spain.ORCID 0000-0002-9805-9523
Armando TorresNephrology Department, Hospital Universitario de Canarias, Instituto de Tecnologías Biomédicas, Universidad La Laguna, REDinREN (RD16/0009/0031), E-38320 Tenerife, Spain.
Mariano RodriguezNephrology Department, Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, RICORS2040 (RD21/0005/0008), E-14004 Cordoba, Spain.
Domingo HernandezNephrology Department, Hospital Universitario Regional de Málaga, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma BIONAND, RICORS2040 (RD21/0005/0012), E-29010 Malaga, Spain.

Funding

Instituto de Salud Carlos III ICI21/00042Instituto de Salud Carlos III PI17/02043Instituto de Salud Carlos III PI21/00251Instituto de Salud Carlos III RD16/0009/0006Instituto de Salud Carlos III RD16/0009/0031Instituto de Salud Carlos III RD21/0005/0001Instituto de Salud Carlos III RD21/0005/0008Instituto de Salud Carlos III RD21/0005/0012MICINN Ramon y Cajal program RYC2018-024461-I
6 · The paper itself

Abstract

We investigated the evolution of serum klotho (s-Kl) and FGF-23 during the first two years post-kidney transplantation (KT), considering the cold ischemia time (CIT), glomerular filtration rate (GFR) and graft subclinical inflammation (SCI). We undertook a prospective, cohort, multicenter study of consecutive patients between April 2018 and January 2021 (with follow-up at 24 months). Subgroups were analyzed according to the median CIT (<14 vs. ≥14 h), the median GFR (≤40 vs. >40 mL/min/1.73 m

Indexed as

cold ischemia timegraft functiongraft subclinical inflammationkidney transplantserum FGF-23 levelsserum klotho levels

Identifiers

PMID37445521
PMCPMC10342325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.