Evidence map›Paper›PMID 37445506›Full record

ArticleJournal of clinical medicine2023

Interleukin 12 in the Acute Phase of the Immune Response after Excimer Laser Treatment.

Mirko Resan, Zeljka Cvejic, Igor Pancevski, Gabriele Thumann, Martina Kropp, Ivo Guber, Dragana Ristic, Danilo Vojvodic, Bojan Pajic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Thermal load management in photorefractive keratectomy: a comprehensive review of cooling strategies.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mirko ResanEye Clinic, Military Medical Academy, 11000 Belgrade, Serbia.
Zeljka CvejicDepartment of Physics, Faculty of Sciences, University of Novi Sad, 21000 Novi Sad, Serbia.ORCID 0000-0002-8218-4899
Igor PancevskiEye Clinic, Military Medical Academy, 11000 Belgrade, Serbia.ORCID 0000-0001-6382-8161
Gabriele ThumannDivision of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, 1205 Geneva, Switzerland.
Martina KroppDivision of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, 1205 Geneva, Switzerland.ORCID 0000-0001-6861-5851
Ivo GuberDivision of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, 1205 Geneva, Switzerland.ORCID 0000-0002-5125-8840
Dragana RisticEye Clinic, Military Medical Academy, 11000 Belgrade, Serbia.
Danilo VojvodicFaculty of Medicine of the Military Medical Academy, University of Defense, 11000 Belgrade, Serbia.ORCID 0000-0001-9308-3076
Bojan PajicFaculty of Medicine of the Military Medical Academy, University of Defense, 11000 Belgrade, Serbia.ORCID 0000-0003-1987-6232
Military Medical Academy · RSUniversity of Geneva · CHUniversity Hospital of Geneva · CHUniversity of Novi Sad · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe aim of the research was to investigate the differences in the concentrations of IL-12, IL-4, IL-10, and IFN-γ in tears after LASIK and PRK procedures. MATERIALS AND

methodsThe study included 68 myopic eyes up to -3.0 D refractive spherical equivalent, divided into two groups: Group 1 LASIK (

resultsIL-4 levels 1 h after treatment did not differ between LASIK and PRK (

conclusionsIL-4 concentration shows a significantly higher value in the LASIK group than in the PRK group after 24 h. IL-10 and IL-12p70 levels increase one hour after surgery in both groups. After 24 h, the IL-10 levels remain elevated in the LASIK group, and the IL-12p70 levels remain elevated in the PRK group. Thus, LASIK and PRK procedures show different inflammatory dynamics.

Indexed as

corneal wound healingexcimer laserIL-10IL-12IL-4LASIKPRKtears

Identifiers

PMID37445506
PMCPMC10342327
OpenAlexW4383104069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.