Evidence map›Paper›PMID 37445504›Full record

ArticleJournal of clinical medicine2023

Hybrid Molecules of Benzylguanidine and the Alkylating Group of Melphalan: Synthesis and Effects on Neuroblastoma Cells.

Gernot Bruchelt, Chihab Klose, Matthias Lischka, Marietta Brandes, Rupert Handgretinger, Reinhard Brueckner

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gernot BrucheltChildren's University Hospital, Hoppe-Seyler-Str. 1, D-72076 Tuebingen, Germany.
Chihab KloseChildren's University Hospital, Hoppe-Seyler-Str. 1, D-72076 Tuebingen, Germany.
Matthias LischkaInstitute of Organic Chemistry, Albert-Ludwigs-University, Albertstr. 21, D-79104 Freiburg, Germany.
Marietta BrandesChildren's University Hospital, Hoppe-Seyler-Str. 1, D-72076 Tuebingen, Germany.
Rupert HandgretingerChildren's University Hospital, Hoppe-Seyler-Str. 1, D-72076 Tuebingen, Germany.
Reinhard BruecknerInstitute of Organic Chemistry, Albert-Ludwigs-University, Albertstr. 21, D-79104 Freiburg, Germany.
University Children's Hospital Tübingen · DEUniversity of Freiburg · DE

Funding

Deutsche Forschungsgemeinschaft HA 2386/2-1 and BR 881/9-1
6 · The paper itself

Abstract

The therapy of neuroblastoma relies, amongst other things, on administering chemotherapeutics and radioactive compounds, e.g., the (

Indexed as

melphalan benzylguanidine hybrids (MBGs)melphalan (M)(meta-iodobenzyl)guanidine (mIBG)neuroblastomanoradrenaline transporter (NAT)organic cation transporter (OCT)

Identifiers

PMID37445504
PMCPMC10342853
OpenAlexW4383104075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.