Evidence map›Paper›PMID 37445452›Full record

ArticleJournal of clinical medicine2023

Intimal CD31-Positive Relative Surfaces Are Associated with Systemic Inflammatory Markers and Maturation of Arteriovenous Fistula in Dialysis Patients.

Réka Kaller, Eliza Russu, Emil Marian Arbănași, Adrian Vasile Mureșan, Márk Jakab, Claudiu Constantin Ciucanu, Eliza Mihaela Arbănași, Bogdan Andrei Suciu, Ioan Hosu, Liliana Demian and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Réka KallerClinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.
Eliza RussuClinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.
Emil Marian ArbănașiClinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.ORCID 0000-0002-1664-8130
Adrian Vasile MureșanClinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.
Márk JakabFaculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.ORCID 0009-0004-8687-4311
Claudiu Constantin CiucanuClinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.
Eliza Mihaela ArbănașiFaculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.ORCID 0000-0003-1281-3749
Bogdan Andrei SuciuDepartment of Anatomy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.
Ioan HosuDepartment of Nephrology, Mures County Emergency Hospital, 540136 Targu Mures, Romania.
Liliana DemianCenter of Advanced Medical and Pharmaceutical Research, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.
Emőke HorváthDepartment of Pathology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · ROSpitalul Clinic Judetean de Urgenta Târgu Mureş · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArteriovenous fistula dysfunction is a widely disputed subject in the scientific literature on end-stage kidney disease (ESKD). The main cause of mortality and morbidity in these patients is the non-maturation or dysfunction of the arteriovenous fistula. Despite the many complications, the native arteriovenous fistula remains the gold standard in the treatment of these patients requiring renal replacement. This study aims to discuss the predictive role of some systemic inflammatory biomarkers (NLR, PLR, SII, IL-6), intimal hyperplasia, and neoangiogenesis (characterized by intimal-media CD31-positive relative surface) in arteriovenous fistula maturation failure.

methodsThe present study was designed as an observational, analytical, and prospective study which included patients diagnosed with ESKD with indications of radio-cephalic arteriovenous fistula (RCAVF). Demographic data, comorbidities, preoperative laboratory data and histological/digital morphometry analysis results were processed. The patients included were divided into two groups based on their AVF maturation status at 8 weeks: "Maturation" (Group 1) and "Failed Maturation" (Group 2).

resultsThere was no difference in the demographic data. In terms of comorbidities, the second group had a greater incidence of heart failure (

conclusionsHeart failure, peripheral artery disease, obesity, and diabetes, as well as the systemic inflammatory markers (NLR, PLR, SII, IL-6), intimal hyperplasia, and CD31-positive relative surfaces are predictors of arteriovenous fistula maturation failures.

Indexed as

arteriovenous fistulaAVFCD31-positive relative surfacedialysisend-stage kidney diseaseIL-6inflammation

Identifiers

PMID37445452
PMCPMC10342422
OpenAlexW4383047266

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.