Evidence map›Paper›PMID 37445269›Full record

ArticleJournal of clinical medicine2023

Three Doses of COVID-19 Vaccines: A Retrospective Study Evaluating the Safety and the Immune Response in Patients with Multiple Sclerosis.

Giorgia Teresa Maniscalco, Daniele Di Giulio Cesare, Valerio Liguori, Valentino Manzo, Elio Prestipino, Simona Salvatore, Maria Elena Di Battista, Ornella Moreggia, Antonio Rosario Ziello, Vincenzo Andreone and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Giorgia Teresa ManiscalcoMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Daniele Di Giulio CesareMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Valerio LiguoriDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Valentino ManzoMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Elio PrestipinoMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Simona SalvatoreMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Maria Elena Di BattistaMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Ornella MoreggiaMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Antonio Rosario ZielloMultiple Sclerosis Regional Center, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Vincenzo AndreoneNeurological Clinic and Stroke Unit, "A. Cardarelli" Hospital, 80131 Naples, Italy.
Cristina ScavoneDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-9216-922X
Annalisa CapuanoDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of the mass immunization of patients with multiple sclerosis (MS), many data on the efficacy and safety of COVID-19 vaccines have been produced. Considering that MS is an autoimmune disease and that some disease-modifying therapies (DMTs) could decrease the antibody response against COVID-19 vaccines, we carried out this retrospective study with the aim to evaluate the safety of these vaccines in terms of AEFI occurrence and the antibody response after MS patients had received the third dose. Two hundred and ten patients (64.8% female; mean age: 46 years) received the third dose of the mRNA-based COVID-19 vaccine and were included in the study. Third doses were administered from October 2021 to January 2022. The majority of patients (

Indexed as

AEFICOVID-19mRNA-based vaccinemultiple sclerosisobservational studysafetythree doses

Identifiers

PMID37445269
PMCPMC10342738
OpenAlexW4382060808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.