Evidence map›Paper›PMID 37445243›Full record

ReviewJournal of clinical medicine2023

Computer-Aided Detection for Pancreatic Cancer Diagnosis: Radiological Challenges and Future Directions.

Mark Ramaekers, Christiaan G A Viviers, Boris V Janssen, Terese A E Hellström, Lotte Ewals, Kasper van der Wulp, Joost Nederend, Igor Jacobs, Jon R Pluyter, Dimitrios Mavroeidis and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. 3D Modelling for Preoperative Planning, Intraoperative Navigation, and Training in Pancreatic Surgery: A Systematic Review.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Review
  2. Article
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  6. Toward diffusion MRI in the diagnosis and treatment of pancreatic cancer.Medical oncology (Northwood, London, England) · 2025
    Review
  7. Review
  8. Article
  9. Article
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  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Mark RamaekersDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0003-2120-7230
Christiaan G A ViviersDepartment of Electrical Engineering, Eindhoven University of Technology, 5612 AZ Eindhoven, The Netherlands.ORCID 0000-0001-6455-0288
Boris V JanssenDepartment of Surgery, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-5678-1510
Terese A E HellströmDepartment of Electrical Engineering, Eindhoven University of Technology, 5612 AZ Eindhoven, The Netherlands.ORCID 0009-0008-1521-4614
Lotte EwalsDepartment of Radiology, Catharina Cancer Institute, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.
Kasper van der WulpDepartment of Radiology, Catharina Cancer Institute, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.
Joost NederendDepartment of Radiology, Catharina Cancer Institute, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0002-9905-5866
Igor JacobsDepartment of Hospital Services and Informatics, Philips Research, 5656 AE Eindhoven, The Netherlands.
Jon R PluyterDepartment of Experience Design, Philips Design, 5656 AE Eindhoven, The Netherlands.
Dimitrios MavroeidisDepartment of Data Science, Philips Research, 5656 AE Eindhoven, The Netherlands.
Fons van der SommenDepartment of Electrical Engineering, Eindhoven University of Technology, 5612 AZ Eindhoven, The Netherlands.ORCID 0000-0002-3593-2356
Marc G BesselinkDepartment of Surgery, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Misha D P LuyerDepartment of Surgery, Catharina Cancer Institute, Catharina Hospital Eindhoven, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0002-9483-1520
E/MTIC Oncology Collaborative Group
Radboud University Nijmegen · NLEindhoven University of Technology · NLPhilips (Netherlands) · NLAmsterdam University Medical Centers · NL

Funding

Eindhoven AI Systems Institute (EAISI) RVO characteristic TKI2112P08
6 · The paper itself

Abstract

Radiological imaging plays a crucial role in the detection and treatment of pancreatic ductal adenocarcinoma (PDAC). However, there are several challenges associated with the use of these techniques in daily clinical practice. Determination of the presence or absence of cancer using radiological imaging is difficult and requires specific expertise, especially after neoadjuvant therapy. Early detection and characterization of tumors would potentially increase the number of patients who are eligible for curative treatment. Over the last decades, artificial intelligence (AI)-based computer-aided detection (CAD) has rapidly evolved as a means for improving the radiological detection of cancer and the assessment of the extent of disease. Although the results of AI applications seem promising, widespread adoption in clinical practice has not taken place. This narrative review provides an overview of current radiological CAD systems in pancreatic cancer, highlights challenges that are pertinent to clinical practice, and discusses potential solutions for these challenges.

Indexed as

artificial intelligenceclinical implementationcomputer-aided detectiondiagnosticspancreatic ductal adenocarcinomaradiological imaging

Identifiers

PMID37445243
PMCPMC10342462
OpenAlexW4381741324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.