Evidence map›Paper›PMID 37444552›Full record

ReviewCancers2023

Transperineal US-MRI Fusion-Guided Biopsy for the Detection of Clinical Significant Prostate Cancer: A Systematic Review and Meta-Analysis Comparing Cognitive and Software-Assisted Technique.

Giacomo Maria Pirola, Daniele Castellani, Luca Orecchia, Carlo Giulioni, Marilena Gubbiotti, Emanuele Rubilotta, Martina Maggi, Jeremy Yuen-Chun Teoh, Vineet Gauhar, Angelo Naselli

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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  9. Micro-ultrasound transperineal prostate biopsy as an alternative to MRI-US fusion transrectal biopsy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Giacomo Maria PirolaDepartment of Urology, San Giuseppe Hospital, IRCCS Multimedica, 20123 Milano, Italy.ORCID 0000-0002-4209-8670
Daniele CastellaniDepartment of Urology, University Hospital "Ospedali Riuniti", Polytechnic University of Marche Region, 60131 Ancona, Italy.ORCID 0000-0001-7354-9190
Luca OrecchiaUrology Unit, Fondazione PTV Policlinico Tor Vergata University Hospital, 00133 Rome, Italy.ORCID 0000-0001-8376-5380
Carlo GiulioniDepartment of Urology, University Hospital "Ospedali Riuniti", Polytechnic University of Marche Region, 60131 Ancona, Italy.ORCID 0000-0001-9934-4011
Marilena GubbiottiDepartment of Urology, Usl Toscana Sud Est, San Donato Hospital, 52100 Arezzo, Italy.ORCID 0000-0002-3486-1226
Emanuele RubilottaDepartment of Urology, A.O.U.I. Verona University, 37129 Verona, Italy.
Martina MaggiMaternal Infant and Urologic Sciences, Policlinico Umberto I Hospital, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0003-4672-850X
Jeremy Yuen-Chun TeohDepartment of Surgery, S.H. Ho Urology Center, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-9361-2342
Vineet GauharDepartment of Urology, Ng Teng Fong General Hospital, National University Health System, Singapore 119074, Singapore.ORCID 0000-0002-3740-7141
Angelo NaselliDepartment of Urology, San Giuseppe Hospital, IRCCS Multimedica, 20123 Milano, Italy.
Marche Polytechnic University · ITMultiMedica · ITChinese University of Hong Kong · HKNg Teng Fong General Hospital · SGOspedale San Donato · ITPoliclinico Tor Vergata · ITPoliclinico Umberto I · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to find potential differences in clinically significant prostate cancer (csPCa) detection rates between transperineal software-assisted fusion biopsy (saFB) and cognitive fusion biopsies (cFB).

methodsA systematic review of the literature was performed to identify comparative studies using PubMed, EMBASE, and Scopus according to the PICOS criteria. Cancer detection and complication rates were pooled using the Cochran-Mantel-Haenszel method with the random effect model and reported as odds ratios (ORs), 95% confidence intervals (CI), and

resultsEight studies were included for the meta-analysis, including 1149 cases in software-based and 963 cases in cognitive fusion biopsy. The detection rates of csPCa were similar between the two groups (OR 1.01, 95% CI 0.74-1.37,

conclusionThere is no actual evidence of the superiority of saFB over cFB in terms of the csPCa detection rate. Operator experience and software availability can drive the choice of one fusion technique over the other.

Indexed as

clinically significant prostate cancermagnetic resonance imagingprostate biopsyprostate cancertransperineal prostate biopsyUS-MRI fusion biopsy

Identifiers

PMID37444552
PMCPMC10341093
OpenAlexW4382982362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.