ArticleCancers2023
Spectrum and Frequency of Germline
Open access · goldAbstract read
In one paragraph
Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
81 authors at 20 institutions in 19 countries.
Gisella FiglioliGenome Diagnostics Program, IFOM ETS-The AIRC Institute of Molecular Oncology, 20139 Milan, Italy.ORCID 0000-0002-0740-1363
Amandine BillaudGenome Diagnostics Program, IFOM ETS-The AIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Qin WangCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
Manjeet K BollaCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
Joe DennisCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.ORCID 0000-0003-4591-1214
Michael LushCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
Anders KvistDivision of Oncology, Department of Clinical Sciences Lund, Lund University, 22185 Lund, Sweden.ORCID 0000-0002-1358-0695
Muriel A AdankThe Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Family Cancer Clinic, 1066 CX Amsterdam, The Netherlands.
Thomas U AhearnDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD 20892, USA.
Natalia N AntonenkovaN.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040 Minsk, Belarus.
Päivi AuvinenTranslational Cancer Research Area, University of Eastern Finland, 70210 Kuopio, Finland.
Sabine BehrensDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0002-9714-104X
Marina BermishevaInstitute of Biochemistry and Genetics of the Ufa Federal Research Centre of the Russian Academy of Sciences, 450054 Ufa, Russia.
Natalia V BogdanovaN.N. Alexandrov Research Institute of Oncology and Medical Radiology, 223040 Minsk, Belarus.ORCID 0000-0002-9736-4593
Stig E BojesenCopenhagen General Population Study, Copenhagen University Hospital, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Bernardo BonanniDivision of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-3589-2128
Thomas BrüningInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), 44789 Bochum, Germany.
Nicola J CampDepartment of Internal Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0002-4788-1998
Archie CampbellCentre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK.ORCID 0000-0003-0198-5078
Jose E CastelaoOncology and Genetics Unit, Instituto de Investigación Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, 36312 Vigo, Spain.
Melissa H CessnaIntermountain Health, Salt Lake City, UT 84111, USA.
Nbcs CollaboratorsDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital-Radiumhospitalet, 0379 Oslo, Norway.
Kamila CzeneDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 76 Stockholm, Sweden.
Peter DevileeDepartment of Pathology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-8023-2009
Thilo DörkGynaecology Research Unit, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-9458-0282
Mikael ErikssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 76 Stockholm, Sweden.ORCID 0000-0001-8135-4270
Peter A FaschingDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany.ORCID 0000-0003-4885-8471
Henrik FlygerDepartment of Breast Surgery, Copenhagen University Hospital, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Marike GabrielsonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 76 Stockholm, Sweden.
Manuela Gago-DominguezInstituto de Investigación Sanitaria de Santiago de Compostela (FIDIS) Foundation, IDIS Cancer Genetics and Epidemiology Group, Genomic Medicine Group, Complejo Hospitalario Universitario de Santiago, SERGAS, 15706 Santiago de Compostela, Spain.
Montserrat García-ClosasDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD 20892, USA.
Gord GlendonLunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Fred A. Litwin Center for Cancer Genetics, Toronto, ON M5G 1X5, Canada.
Encarna B Gómez GarciaDepartment of Clinical Genetics, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands.
Anna González-NeiraHuman Genotyping Unit-CeGen, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.ORCID 0000-0002-5421-2020
Felix GrassmannDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 76 Stockholm, Sweden.
Pascal GuénelCESP U1018, Inserm "Exposome, Heredity, Cancer and Health" Team, UVSQ, University Paris-Saclay, Gustave Roussy, 94805 Villejuif, France.
Eric HahnenCenter for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Ute HamannGerman Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, 69120 Heidelberg, Germany.ORCID 0000-0001-6705-7624
Peter HillemannsGynaecology Research Unit, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0001-9829-3531
Maartje J HooningDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Reiner HoppeDr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.
Anthony HowellDivision of Cancer Sciences, University of Manchester, Manchester M13 9PL, UK.
Keith HumphreysDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 76 Stockholm, Sweden.ORCID 0000-0002-7458-8252
kConFab InvestigatorsResearch Department, Peter MacCallum Cancer Center, Melbourne, VIC 3000, Australia.
Anna JakubowskaDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University in Szczecin, 71-252 Szczecin, Poland.ORCID 0000-0002-5650-0501
Elza K KhusnutdinovaInstitute of Biochemistry and Genetics of the Ufa Federal Research Centre of the Russian Academy of Sciences, 450054 Ufa, Russia.
Vessela N KristensenInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450 Oslo, Norway.
Annika LindblomDepartment of Molecular Medicine and Surgery, Karolinska Institutet, 171 76 Stockholm, Sweden.
Maria A LoizidouDepartment of Cancer Genetics, Therapeutics and Ultrastructural Pathology, The Cyprus Institute of Neurology & Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0003-4503-7758
Jan LubińskiDepartment of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University in Szczecin, 71-252 Szczecin, Poland.
Arto MannermaaTranslational Cancer Research Area, University of Eastern Finland, 70210 Kuopio, Finland.
Tabea MaurerCancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Dimitrios MavroudisDepartment of Medical Oncology, University Hospital of Heraklion, 711 10 Heraklion, Greece.
William G NewmanDivision of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-6382-4678
Nadia ObiUniversity Medical Center Hamburg-Eppendorf, Institute for Medical Biometry and Epidemiology, 20246 Hamburg, Germany.ORCID 0000-0002-0903-9142
Mihalis I PanayiotidisDepartment of Cancer Genetics, Therapeutics and Ultrastructural Pathology, The Cyprus Institute of Neurology & Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0002-1450-3552
Paolo RadiceUnit of 'Predictive Medicine: Molecular Bases of Genetic Risk', Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.ORCID 0000-0001-6298-4111
Muhammad U RashidGerman Cancer Research Center (DKFZ), Molecular Genetics of Breast Cancer, 69120 Heidelberg, Germany.ORCID 0000-0002-7684-3122
Valerie RheniusCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Matthias RuebnerDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany.
Emmanouil SaloustrosDepartment of Oncology, University Hospital of Larissa, 411 10 Larissa, Greece.ORCID 0000-0002-0485-0120
Elinor J SawyerKing's College London, School of Cancer & Pharmaceutical Sciences, Comprehensive Cancer Centre, Guy's Campus, London SE1 9RT, UK.
Marjanka K SchmidtDivision of Molecular Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-2228-429X
Rita K SchmutzlerCenter for Familial Breast and Ovarian Cancer, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Mitul ShahCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Melissa C SoutheyPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
Ian TomlinsonCancer Research Centre, The University of Edinburgh, Edinburgh EH4 2XU, UK.
Thérèse TruongCESP U1018, Inserm "Exposome, Heredity, Cancer and Health" Team, UVSQ, University Paris-Saclay, Gustave Roussy, 94805 Villejuif, France.
Elke M van VeenDivision of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0001-8618-2332
Camilla WendtDepartment of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, 118 83 Stockholm, Sweden.
Xiaohong R YangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Department of Health and Human Services, Bethesda, MD 20892, USA.
Kyriaki MichailidouCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.ORCID 0000-0001-7065-1237
Alison M DunningCentre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.
Paul D P PharoahCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.ORCID 0000-0001-8494-732X
Douglas F EastonCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
Irene L AndrulisLunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Fred A. Litwin Center for Cancer Genetics, Toronto, ON M5G 1X5, Canada.ORCID 0000-0002-4226-6435
D Gareth EvansDivision of Evolution, Infection and Genomics, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-8482-5784
Antoinette HollestelleDepartment of Medical Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1166-1966
Jenny Chang-ClaudeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0001-8919-1971
Roger L MilnePrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
Paolo PeterlongoGenome Diagnostics Program, IFOM ETS-The AIRC Institute of Molecular Oncology, 20139 Milan, Italy.ORCID 0000-0001-6951-6855
University of Cambridge · GBKarolinska Institutet · SEUniversität Hamburg · DEGerman Cancer Research Center · DEInserm · FRNational Institutes of Health · USThe University of Melbourne · AUIFOM · ITLeiden University Medical Center · NLMount Sinai Hospital · CAOslo University Hospital · NOUniversity of Eastern Finland · FICedars-Sinai Medical Center · USGentofte Hospital · DKKarolinska University Hospital · SEManchester Academic Health Science Centre · GBMedizinische Hochschule Hannover · DEDr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology · DEEdinburgh Cancer Research · GBEuropean Institute of Oncology · IT
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MCore-001U01CA164920 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Irene Andrulis, Sarah Violet Colonna · 2018 to 2026
$17.0MThe Nashville Breast Health StudyR01CA100374 · NCI · VANDERBILT UNIVERSITY · PI ZHENG, WEI · 2004 to 2009
$4.2MShared Genomic Segment Analysis and Tumor Subtyping in High-Risk BrCa PedigreesR01CA163353 · NCI · UNIVERSITY OF UTAH · PI CAMP, NICOLA J. · 2012 to 2016
$2.9MAdmixture Mapping for Breast Cancer in LatinasR01CA120120 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZIV, ELAD · 2007 to 2011
$2.8MGenetics of mammographic density and breast cancer risk in LatinasK24CA169004 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZIV, ELAD · 2012 to 2021
$1.8MFondazione Umberto Veronesi naItalian Association for Cancer Research IG22860NCI NIH HHS K24 CA169004NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA100374NCI NIH HHS R01 CA120120NCI NIH HHS R01 CA163353NCI NIH HHS U01 CA164920Wellcome Trust
Abstract
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Indexed as
breast cancer predispositionbreast cancer risk factorsFANCM PTVs spectrumprotein truncating variantsPTVs
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.