Evidence map›Paper›PMID 37444405›Full record

ReviewCancers2023

Oral Mucosa in Cancer Patients-Putting the Pieces Together: A Narrative Review and New Perspectives.

Jose Manuel Reuss, Laura Alonso-Gamo, Mariola Garcia-Aranda, Debora Reuss, Manuel Albi, Beatriz Albi, Debora Vilaboa, Beatriz Vilaboa

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. The prevalence of oral mucositis after radiotherapy in patients with Head and Neck Cancer and its associated factors: a meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Jose Manuel ReussDepartment of Postgraduate Prosthodontics, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Laura Alonso-GamoDepartment of Pediatrics, Hospital Infanta Cristina, 28981 Madrid, Spain.
Mariola Garcia-ArandaCentro Integral Oncológico Clara Campal, Department of Oncologic Radiotherapy, Hospital Universitario Sanchinarro, 28050 Madrid, Spain.
Debora ReussLecturer Dental School, Universidad San Pablo CEU, 28003 Madrid, Spain.
Manuel AlbiDepartment of Gynecology and Obstetrics, Quironsalud Group Public Hospitals, 28223 Madrid, Spain.
Beatriz AlbiDepartment of Gynecology and Obstetrics, Hospital Universitario Fundación Jiménez Díaz, 28040 Madrid, Spain.
Debora VilaboaAesthetic Dentistry Department, Universidad San Pablo CEU, 28003 Madrid, Spain.
Beatriz VilaboaClínica Vilaboa, 28001 Madrid, Spain.
Universidad San Pablo CEU · ESHospital Universitario Fundación Jiménez Díaz · ESHospital Universitario HM Sanchinarro · ESHospital Universitario Infanta Cristina · ESHospital Universitario Quirónsalud Madrid · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral mucosa is a key player in cancer patients and during cancer treatment. The increasing prevalence of cancer and cancer-therapy-associated side effects are behind the major role that oral mucosa plays in oncological patients. Oral mucositis is a debilitating severe complication caused by the early toxicity of chemo and/or radiotherapy that can restrict treatment outcome possibilities, even challenging a patient's survival. It has been referred to as the most feared cancer treatment complication. Predictive variables as to who will be affected, and to what extent, are still unclear. Additionally, oral mucositis is one of the sources of the increasing economic burden of cancer, not only for patients and their families but also for institutions and governments. All efforts should be implemented in the search for new approaches to minimize the apparently ineluctable outburst of oral mucositis during cancer treatment. New perspectives derived from different approaches to explaining the interrelation between oral mucositis and the oral microbiome or the similarities with genitourinary mucosa may help elucidate the biomolecular pathways and mechanisms behind oral mucosa cancer-therapy-related toxicity, and what is more important is its management in order to minimize treatment side effects and provide enhanced cancer support.

Indexed as

antioxidantbreast cancer survivorscancer supportcancer toxicityhead and neck cancermicrobiome boostmucositisoral mucosasaliactivevagina

Identifiers

PMID37444405
PMCPMC10340546
OpenAlexW4381741950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.