ReviewAnimals : an open access journal from MDPI2023
Current Insights in the Repeat Breeder Cow Syndrome.
Review in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed.
- Characterization of the vaginal bacterial microbiota of sheep exhibiting abortion or repeat breeder syndrome.Veterinary and animal science · 2026Article
- Effect of post-insemination GnRH analogue administration on pregnancy rates in repeat-breeder cows: Comparison of dosage and frequency.The Journal of reproduction and development · 2026Article
- Delayed ovulation in cattle: Physiological mechanisms, diagnostic approaches, and reproductive management strategies.Veterinary world · 2026Article
- Bisphenol F-Associated Repeated Breeding Syndrome in Cows: Epidemiological Evidence and Protective Effects of Phillyrin Against Granulosa Cell Injury.Veterinary sciences · 2026Article
- Reproductive challenges in Indian dairy farming: an analysis of repeat breeding and infertility in Tamil Nadu.Tropical animal health and production · 2026Article
- Vaginal Microbiota Composition and Its Relationship with Fertility in Repeat Breeder Dairy Cows.Biology · 2026Article
- Comparative analysis of delayed ovulation and associated ovarian patterns in the Ongole crossbred cattle.Open veterinary journal · 2026Article
- Knowledge, Attitudes, and Practices of Smallholder Dairy Cattle Farmers in Tanzania: A Cross-Sectional Survey on Cattle Infertility.Veterinary sciences · 2025Article
- Differences in the Gut Microbiota in Long-Term Infertile Holstein Repeat Breeder Cows and Healthy Fertile Holstein Cows.Animals : an open access journal from MDPI · 2025Article
- Prevalence and risk factors of repeat breeding in dairy cows in Cendana District, Enrekang Regency, South Sulawesi, Indonesia.Open veterinary journal · 2025Article
- Effects of Two Hormonal Protocols for FTAI on the Fertility of Repeat Cows.International journal of molecular sciences · 2025Article
- Reproductive disorders in Simmental cattle: Enhancing fertility through a hormonal protocol.Open veterinary journal · 2025Article
- Impact of Season and OvSynch + GnRH on Day 5 After Artificial Insemination (AI) on the Heat Detection and Conception Rates of Cooled High-Yielding Holstein Cows.Animals : an open access journal from MDPI · 2025Article
- A Prospective Study of the Prevalence and Predictive Risk Factors of Repeat Breeder Syndrome in Dairy Cattle in the North of Spain.Animals : an open access journal from MDPI · 2025Article
- Advances in Dairy Cattle Reproduction-A Foreword.Animals : an open access journal from MDPI · 2024Article
- Tryptophan regulates the expression of IGFBP1 in bovine endometrial epithelial cells in vitro via the TDO2-AHR pathway.BMC veterinary research · 2024Article
- Evaluation of the effect of sustained-release progesterone injection on the expression of interferon-related genes in repeat-breeder dairy cows.Veterinary medicine and science · 2024Article
- Inflammatory uterine microenvironment in long-term infertility repeat breeder cows compared with normal fertile cows.Veterinary and animal science · 2024Article
- Customized modified therapies for ovarian cyst and persistent follicle followed with TAI in early postpartum dairy cows.Open veterinary journal · 2024Article
- Impact of presynchronization and Ovsynch on early postpartum ovarian activity and fertility of dairy cows in Libya.Open veterinary journal · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cows can have difficulties becoming pregnant, and in certain cases, these reproductive failures do not have an evident cause. Furthermore, when these failures are repeated three or more times with estrous cycles of normal duration and in the absence of evident clinical signs, it is considered repeat breeder cow (RBC) syndrome. A substantive incidence of RBC syndrome has been reported all over the world, which severely affects the farm economy. This paper reviews those studies particularly focused on RBC syndrome from 2000 to 2023 but also includes consolidated information until this date. Hormonal imbalances, undetectable oviductal or uterine defects, or poor oocyte or embryo quality have been reported as causes of RBC syndrome, while subclinical endometritis has been considered a relevant causal agent. However, it is unresolved why this condition is recurrent in certain animals, despite the implementation of corrective management actions or treatments. Recent studies evaluate the putative role of certain genes, factors, hormones, or proteins in the pathogenesis of RBC syndrome. Numerous risk factors contribute to the appearance of this syndrome, and some of them could be mitigated to partially prevent this infertility, while others cannot be changed. Due to the complexity of this syndrome, it is important to increase knowledge about the mechanisms involved, develop new diagnostic tools to differentiate causal agents, and implement new treatments to restore fertility. There is consensus about the huge repercussions of this syndrome on farm profitability, but further studies are now needed to describe its economic impact.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.