Evidence map›Paper›PMID 37443900›Full record

ReviewAnimals : an open access journal from MDPI2023

Pre-Implantation Bovine Embryo Evaluation-From Optics to Omics and Beyond.

R A Chanaka Rabel, Paula V Marchioretto, Elizabeth A Bangert, Kenneth Wilson, Derek J Milner, Matthew B Wheeler

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Toward Practical Embryo Genomic Selection in Cattle: An Optimized Workflow Enabling High-Accuracy Breeding Value Prediction Without Compromising Embryo Survival.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. In vitro production significantly reduces metabolic differences among bovine embryos.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R A Chanaka RabelDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0009-0001-2763-8819
Paula V MarchiorettoDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0009-0002-8228-2170
Elizabeth A BangertDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Kenneth WilsonDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Derek J MilnerDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Matthew B WheelerDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-5589-357X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 80% of the ~1.5 million bovine embryos transferred in 2021 were in vitro produced. However, only ~27% of the transferred IVP embryos will result in live births. The ~73% pregnancy failures are partly due to transferring poor-quality embryos, a result of erroneous stereomicroscopy-based morphological evaluation, the current method of choice for pre-transfer embryo evaluation. Numerous microscopic (e.g., differential interference contrast, electron, fluorescent, time-lapse, and artificial-intelligence-based microscopy) and non-microscopic (e.g., genomics, transcriptomics, epigenomics, proteomics, metabolomics, and nuclear magnetic resonance) methodologies have been tested to find an embryo evaluation technique that is superior to morphologic evaluation. Many of these research tools can accurately determine embryo quality/viability; however, most are invasive, expensive, laborious, technically sophisticated, and/or time-consuming, making them futile in the context of

Indexed as

assisted reproductive technologiesbeef cattle embryo stagingbovine embryo evaluationbovine embryo gradingbovine embryo transferdairy cattle blastocyst morphological analysisin vitro fertilizationin vitro productionin vivo derived embryospre-implantation embryo quality

Identifiers

PMID37443900
PMCPMC10339960

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.