ReviewAnimals : an open access journal from MDPI2023
Influence of Different Light Spectra on Melatonin Synthesis by the Pineal Gland and Influence on the Immune System in Chickens.
Review in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Physiological role of light modulation on poultry production, reproductions and welfare: a-systematic review.Veterinary research communications · 2026Pooled it
- Monochromatic Blue Light Enhances Antioxidant Status and Remodels the Gut Microbiome in Association with Increased Plasma Melatonin in Broiler Chickens.Antioxidants (Basel, Switzerland) · 2026Article
- Effect of photoperiod duration during incubation on hatch traits, growth, and behavior of Leghorn chicks to 21 days of age.Poultry science · 2026Article
- Photoperiod as a neuroendocrine regulator: A review on pineal-melatonin signaling and physiological plasticity in poultry.Poultry science · 2026Review
- The Effects of a Mixture of Monochromatic Green and Blue Light on Growth Performance and Immune Response in Bursa of Fabricius by Morphometry Using Staining and Immunohistochemistry in Broiler Chickens.Animals : an open access journal from MDPI · 2026Article
- Effects of Monochromatic Light on the Development of Immune Organs, Antioxidant Capacity and Immune Response of Thymus and Bursal of Fabricius in Yangzhou Geese.Animals : an open access journal from MDPI · 2025Article
- The Influence of Different Light Spectra on Broiler Chicken Endocrine Systems and Productivity.Animals : an open access journal from MDPI · 2025Review
- The rhythm of decline: Circadian disruption in neurodegeneration.Journal of food and drug analysis · 2025Review
- Restorative potential of melatonin during treatment of severe scabies in an experimental model.Parasitology research · 2025Article
- Influence of Photoperiod and Exogenous Melatonin on the Maturation and Apoptosis of B Lymphocytes in the Spleen.Bulletin of experimental biology and medicine · 2025Article
- Melatonin as the Missing Link Between Sleep Deprivation and Immune Dysregulation: A Narrative Review.International journal of molecular sciences · 2025Review
- Molecular pathways affecting reproductive efficiency in seasonal breeders: prospects and implications for improving fertility in donkeys.Frontiers in veterinary science · 2025Review
- The Role of Melatonin in the Inflammatory Process in Patients with Hyperglycemia and Leishmania Infection.Biomolecules · 2024Article
- Pharmacotherapeutic Considerations on Telomere Biology: The Positive Effect of Pharmacologically Active Substances on Telomere Length.International journal of molecular sciences · 2024Review
- Green Light Mitigates Cyclic Chronic Heat-Stress-Induced Liver Oxidative Stress and Inflammation via NF-κB Pathway Inhibition in Geese.Antioxidants (Basel, Switzerland) · 2024Article
- Role of Melatonin in Viral, Bacterial and Parasitic Infections.Biomolecules · 2024Review
- Melatonin as a multifunctional modulator: emerging insights into its role in health, reproductive efficiency, and productive performance in livestock.Frontiers in physiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well known that the pineal gland in birds influences behavioural and physiological functions, including those of the immune system. The purpose of this research is to examine the endocrine-immune correlations between melatonin and immune system activity. Through a description of the immune-pineal axis, we formulated the objective to determine and describe: the development of the pineal gland; how light influences secretory activity; and how melatonin influences the activity of primary and secondary lymphoid organs. The pineal gland has the ability to turn light information into an endocrine signal suitable for the immune system via the membrane receptors Mel1a, Mel1b, and Mel1c, as well as the nuclear receptors RORα, RORβ, and RORγ. We can state the following findings: green monochromatic light (560 nm) increased serum melatonin levels and promoted a stronger humoral and cellular immune response by proliferating B and T lymphocytes; the combination of green and blue monochromatic light (560-480 nm) ameliorated the inflammatory response and protected lymphoid organs from oxidative stress; and red monochromatic light (660 nm) maintained the inflammatory response and promoted the growth of pathogenic bacteria. Melatonin can be considered a potent antioxidant and immunomodulator and is a critical element in the coordination between external light stimulation and the body's internal response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.