Evidence map›Paper›PMID 37443687›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Artificial Intelligence in Renal Cell Carcinoma Histopathology: Current Applications and Future Perspectives.

Alfredo Distante, Laura Marandino, Riccardo Bertolo, Alexandre Ingels, Nicola Pavan, Angela Pecoraro, Michele Marchioni, Umberto Carbonara, Selcuk Erdem, Daniele Amparore and 9 more

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Alfredo DistanteDepartment of Urology, Catholic University of the Sacred Heart, 00168 Roma, Italy.ORCID 0000-0002-9952-4212
Laura MarandinoDepartment of Medical Oncology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Riccardo BertoloDepartment of Urology, San Carlo Di Nancy Hospital, 00165 Rome, Italy.ORCID 0000-0003-0260-4601
Alexandre IngelsDepartment of Urology, University Hospital Henri Mondor, APHP (Assistance Publique-Hôpitaux de Paris), 94000 Créteil, France.
Nicola PavanDepartment of Surgical, Oncological and Oral Sciences, Section of Urology, University of Palermo, 90133 Palermo, Italy.ORCID 0000-0001-7355-7625
Angela PecoraroDepartment of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, 10043 Turin, Italy.
Michele MarchioniDepartment of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University of Chieti, 66100 Chieti, Italy.ORCID 0000-0002-1702-4127
Umberto CarbonaraAndrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation-Urology, University of Bari, 70121 Bari, Italy.ORCID 0000-0002-3179-630X
Selcuk ErdemDivision of Urologic Oncology, Department of Urology, Istanbul University Istanbul Faculty of Medicine, Istanbul 34093, Turkey.ORCID 0000-0002-3514-1394
Daniele AmparoreDepartment of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, 10043 Turin, Italy.
Riccardo CampiUrological Robotic Surgery and Renal Transplantation Unit, Careggi Hospital, University of Florence, 50121 Firenze, Italy.ORCID 0000-0001-5237-0888
Eduard RousselDepartment of Urology, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7835-5536
Anna CaliòSection of Pathology, Department of Diagnostic and Public Health, University of Verona, 37134 Verona, Italy.
Zhenjie WuDepartment of Urology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Carlotta PalumboDivision of Urology, Maggiore della Carità Hospital of Novara, Department of Translational Medicine, University of Eastern Piedmont, 13100 Novara, Italy.ORCID 0000-0002-6165-5276
Leonardo D BorregalesDepartment of Urology, Well Cornell Medicine, New York-Presbyterian Hospital, New York, NY 10032, USA.
Peter MuldersDepartment of Urology, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.
Constantijn H J MuselaersDepartment of Urology, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands.
EAU Young Academic Urologists (YAU) Renal Cancer Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is characterized by its diverse histopathological features, which pose possible challenges to accurate diagnosis and prognosis. A comprehensive literature review was conducted to explore recent advancements in the field of artificial intelligence (AI) in RCC pathology. The aim of this paper is to assess whether these advancements hold promise in improving the precision, efficiency, and objectivity of histopathological analysis for RCC, while also reducing costs and interobserver variability and potentially alleviating the labor and time burden experienced by pathologists. The reviewed AI-powered approaches demonstrate effective identification and classification abilities regarding several histopathological features associated with RCC, facilitating accurate diagnosis, grading, and prognosis prediction and enabling precise and reliable assessments. Nevertheless, implementing AI in renal cell carcinoma generates challenges concerning standardization, generalizability, benchmarking performance, and integration of data into clinical workflows. Developing methodologies that enable pathologists to interpret AI decisions accurately is imperative. Moreover, establishing more robust and standardized validation workflows is crucial to instill confidence in AI-powered systems' outcomes. These efforts are vital for advancing current state-of-the-art practices and enhancing patient care in the future.

Indexed as

artificial intelligencekidney cancerpathologyrenal cell carcinoma

Identifiers

PMID37443687
PMCPMC10340141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.