Evidence map›Paper›PMID 37443640›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Sleep-Disordered Breathing and Prognosis after Ischemic Stroke: It Is Not Apnea-Hypopnea Index That Matters.

Lyudmila Korostovtseva, Mikhail Bochkarev, Valeria Amelina, Uliana Nikishkina, Sofia Osipenko, Anastasia Vasilieva, Vladislav Zheleznyakov, Ekaterina Zabroda, Alexey Gordeev, Maria Golovkova-Kucheryavaia and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Lyudmila KorostovtsevaAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Mikhail BochkarevAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.ORCID 0000-0002-7408-9613
Valeria AmelinaAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Uliana NikishkinaMedical Faculty, Pavlov University, 197022 St. Petersburg, Russia.
Sofia OsipenkoAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.ORCID 0000-0003-2944-9904
Anastasia VasilievaAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Vladislav ZheleznyakovAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.ORCID 0000-0001-7934-2852
Ekaterina ZabrodaAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Alexey GordeevAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.ORCID 0000-0001-9916-9022
Maria Golovkova-KucheryavaiaAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Stanislav YanishevskiyAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Yurii SviryaevAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Aleksandra KonradiAlmazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Federal Almazov North-West Medical Research Centre · RUFirst Pavlov State Medical University of St. Petersburg · RUSt Petersburg University · RU

Funding

Russian Science Foundation 21-75-173
6 · The paper itself

Abstract

backgroundSleep-disordered breathing (SDB) is highly prevalent after stroke and is considered to be a risk factor for poor post-stroke outcomes. The aim of this observational study was to evaluate the effect of nocturnal respiratory-related indices based on nocturnal respiratory polygraphy on clinical outcomes (including mortality and non-fatal events) in patients with ischemic stroke.

methodsA total of 328 consecutive patients (181 (55%) males, mean age 65.8 ± 11.2 years old) with confirmed ischemic stroke admitted to a stroke unit within 24 h after stroke onset were included in the analysis. All patients underwent standard diagnostic and treatment procedures, and sleep polygraphy was performed within the clinical routine in the first 72 h after admission. The long-term outcomes were assessed by cumulative endpoint (death of any cause, new non-fatal myocardial infarction, new non-fatal stroke/transient ischemic attack, emergency revascularization, emergency hospitalization due to the worsening of cardiovascular disease). A Cox-regression analysis was applied to evaluate the effects of nocturnal respiratory indices on survival.

resultsThe mean follow-up period comprised 12 months (maximal-48 months). Patients with unfavourable outcomes demonstrated a higher obstructive apnea-hypopnea index, a higher hypoxemia burden assessed as a percent of the time with SpO

conclusionOur study demonstrates that the indices of hypoxemia burden have additional independent predictive value for long-term outcomes (mortality and non-fatal cardiovascular events) after ischemic stroke.

Indexed as

hypoxemia burdenischemic strokesleep-disordered breathingstrokestroke outcome

Identifiers

PMID37443640
PMCPMC10340264
OpenAlexW4382982889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.