Evidence map›Paper›PMID 37443602›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Impact of Dual-Energy Computed Tomography (DECT) Postprocessing Protocols on Detection of Monosodium Urate (MSU) Deposits in Foot Tendons of Cadavers.

Andrea Sabine Klauser, Sylvia Strobl, Christoph Schwabl, Christian Kremser, Werner Klotz, Violeta Vasilevska Nikodinovska, Hannes Stofferin, Yannick Scharll, Ethan Halpern

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Costal cartilage mimics urate on DECT.Skeletal radiology · 2025
    Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Andrea Sabine KlauserDepartment for Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Sylvia StroblDepartment for Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christoph SchwablDepartment for Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-4438-9025
Christian KremserDepartment for Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-6953-935X
Werner KlotzDepartment of Internal Medicine, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Violeta Vasilevska NikodinovskaUniversity Surgical Clinic "St. Naum Ohridski", Faculty of Medicine, Ss. Cyril and Methodius University, 1000 Skopje, North Macedonia.
Hannes StofferinInstitute of Clinical and Functional Anatomy, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-0344-4606
Yannick ScharllDepartment for Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Ethan HalpernJefferson Prostate Diagnostic and Kimmel Cancer Center, Department of Radiology and Urology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Innsbruck Medical University · ATSs. Cyril and Methodius University in Skopje · MKThomas Jefferson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate two different dual-energy computed tomography (DECT) post-processing protocols for the detection of MSU deposits in foot tendons of cadavers with verification by polarizing light microscopy as the gold standard. MATERIAL AND

methodsA total of 40 embalmed cadavers (15 male; 25 female; median age, 82 years; mean, 80 years; range, 52-99; SD ± 10.9) underwent DECT to assess MSU deposits in foot tendons. Two postprocessing DECT protocols with different Hounsfield unit (HU) thresholds, 150/500 (=established) versus 120/500 (=modified). HU were applied to dual source acquisition with 80 kV for tube A and 140 kV for tube B. Six fresh cadavers (4 male; 2 female; median age, 78; mean, 78.5; range 61-95) were examined by DECT. Tendon dissection of 2/6 fresh cadavers with positive DECT 120 and negative DECT 150 studies were used to verify MSU deposits by polarizing light microscopy.

resultsThe tibialis anterior tendon was found positive in 57.5%/100% (DECT 150/120), the peroneus tendon in 35%/100%, the achilles tendon in 25%/90%, the flexor halluces longus tendon in 10%/100%, and the tibialis posterior tendon in 12.5%/97.5%. DECT 120 resulted in increased tendon MSU deposit detection, when DECT 150 was negative, with an overall agreement between DECT 150 and DECT 120 of 80% (

conclusionThe DECT 120 protocol showed a higher sensitivity when compared to DECT 150.

Indexed as

dual-energy computed tomographyfootgoutmonosodium urate depositstendon

Identifiers

PMID37443602
PMCPMC10341184
OpenAlexW4382369574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.