Evidence map›Paper›PMID 37443567›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Analytical Validation of a Novel MicroRNA Panel for Risk Stratification of Cognitive Impairment.

Arzu Kunwar, Kenny Kwabena Ablordeppey, Alidad Mireskandari, Kira Sheinerman, Michael Kiefer, Samuil Umansky, Gyanendra Kumar

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. IsomiR stoichiometry changes as disease biomarkers.Molecular therapy. Nucleic acids · 2025
    Article
  5. MicroRNAs in idiopathic childhood nephrotic syndrome.Clinical and experimental nephrology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arzu KunwarDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.ORCID 0000-0002-8986-1338
Kenny Kwabena AblordeppeyDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.
Alidad MireskandariDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.
Kira SheinermanDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.
Michael KieferDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.
Samuil UmanskyDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.
Gyanendra KumarDiamiR Biosciences Laboratory, 2 Church Street South, Suite B05, New Haven, CT 06519, USA.ORCID 0000-0002-8282-9116

Funding

Early detection of Alzheimer's (MCI stage): Analysis of plasma cell-free miRNAR44AG044860 · NIA · DIAMIR, LLC · PI UMANSKY, SAMUIL R · 2015 to 2022
$8.0M
NIA NIH HHS R44 AG044860NIA NIH HHS R44AG044860
6 · The paper itself

Abstract

We have been developing a novel approach to identify cognitive impairment-related biomarkers by profiling brain-enriched and inflammation-associated microRNA (miRNA) in plasma specimens of cognitively unimpaired and cognitively impaired patients. Here, we present an analytical validation of the novel miRNA panel, CogniMIR

Indexed as

Alzheimer’s disease (AD)analytical validationblood-based molecular diagnosticscognitive impairmentexpression profiling of circulating miRNALNA-based qPCRmicroRNA biomarkersmild cognitive impairment (MCI)neurodegenerative diseasesTaqMan-based qPCR

Identifiers

PMID37443567
PMCPMC10340136
OpenAlexW4382449369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.