Evidence map›Paper›PMID 37443035›Full record

ArticleBiomedical engineering online2023

Preclinical trial of the effectiveness of a safety nasogastric tube to detect the tube position based on tidal volume and pepsin assay results in the gastrointestinal tract of Macaca fascicularis.

Sigit Mohammad Nuzul, Neng Tine Kartinah, Busjra M Nur, Ermita I Ibrahim Ilyas

Abstract read
In one paragraph

Article in Biomedical engineering online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sigit Mohammad NuzulMaster's Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia. sigitmnuzul@gmail.com.
Neng Tine KartinahPhysiology Department, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.
Busjra M NurPhysiology Department, Faculty of Medicine and Health, Universitas Muhammadiyah, Jakarta, Indonesia.
Ermita I Ibrahim IlyasPhysiology Department, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.

Funding

Universitas Indonesia NKB-4182/UN2.RST/ HKP.05.00/2020
6 · The paper itself

Abstract

backgroundTube misplacement into the tracheobronchial tract is associated with pneumothorax in 0.5% of cases. NGT verification only detects the position of the tube at the end of the procedure. Therefore, a safe nasogastric tube (SNGT) was created to detect the NGT position in real time in a simple and inexpensive way. This study aimed to prove the effectiveness of the SNGT prototype in Macaca fascicularis.

resultAn SNGT producing 50% of the TV had 100% sensitivity and specificity in detecting the position of the tube at 100% of the TV, with a sensitivity of 100% and a specificity of 87.5%. There was a significant difference between the movement of the SNGT 50% TV and SNGT 100% TV airbags (p ≤ 0.05). However, there was no significant difference between the accuracy of placement of the 50% TV SNGT, 100% TV SNGT, and conventional NGT (p > 0.05). The pepsin enzyme had better sensitivity (100%) than pH paper (91.66%) in detecting the end-of-procedure tube position. This research has the potential to advance into human clinical trials.

conclusionSNGTs are highly effective in detecting the NGT position inside the respiratory and digestive tracts to prevent misplacement.

Indexed as

Intubation, GastrointestinalPepsin AAnimalsClinical Trials as TopicGastrointestinal TractMacaca fascicularisTidal VolumePepsin AMalpositionNasogastric tubePepsin

Identifiers

PMID37443035
PMCPMC10339581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.