Evidence map›Paper›PMID 37442999›Full record

Trial reportBMC psychiatry2023

Hopefulness among individuals living with schizophrenia and their caregivers in Tanzania: an actor-partner interdependence model.

Alyssa Martinez, Joy Noel Baumgartner, Sylvia Kaaya, Praxeda Swai, Paul S Lawala, Beatrice Thedai, Anna Minja, Jennifer Headley, Joseph R Egger

Erratum issued Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04013932 (Family Psychoeducation for Adults With Psychotic Disorders in Tanzania), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04013932 nacompletednot on this map

Family Psychoeducation for Adults With Psychotic Disorders in Tanzania (Pilot Clinical Trial of KUPAA)

TypeinterventionalSponsorDuke UniversityRan2019 to 2020Enrolled66ConditionsSchizophrenia Spectrum and Other Psychotic Disorders, Mental Disorders, SevereArmsKUPAA Intervention Group (Culturally Tailored Family Psychoeducation)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Alyssa MartinezHarvard Medical School, Department of Global Health & Social Medicine, Boston, MA, USA.
Joy Noel BaumgartnerDuke Global Health Institute, Duke University, Durham, NC, USA.
Sylvia KaayaSchool of Medicine, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.
Praxeda SwaiSchool of Medicine, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.
Paul S LawalaMirembe National Mental Health Hospital, Dodoma, Tanzania.
Beatrice ThedaiMbeya Zonal Referral Hospital, Mbeya, Tanzania.
Anna MinjaSchool of Medicine, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.
Jennifer HeadleyDuke Global Health Institute, Duke University, Durham, NC, USA.
Joseph R EggerDuke Global Health Institute, Duke University, Durham, NC, USA. joseph.egger@duke.edu.
Muhimbili University of Health and Allied Sciences · TZDuke University · USHarvard Global Health Institute · USMbeya University of Science and Technology · TZMuhimbili National Hospital · TZUniversity of North Carolina at Chapel Hill · US

Funding

Family psychoeducation for adults with psychotic disorders in TanzaniaR34MH106663 · NIMH · DUKE UNIVERSITY · PI BAUMGARTNER, JOY NOEL · 2017 to 2019
$644k
NIMH NIH HHS R34 MH106663
6 · The paper itself

Abstract

backgroundHopefulness is a positive orientation or state of mind that can aid in the recovery and treatment of mental illness, as it can have significant impacts on clinical and psychosocial outcomes. As resource-constrained settings work to implement recovery-oriented care, there is a need to better understand hopefulness among people living with schizophrenia (PLWS) and caregivers in their extended family networks. This study seeks to examine the dyadic relationship of hopefulness and its associated correlates among PLWS attending outpatient psychiatric clinics and their caregivers in Tanzania.

methodsThis study utilized baseline and immediate post-intervention data collected as part of a randomized controlled trial testing a culturally tailored model of Family Psychoeducation, KUPAA, in Tanzania. The Herth Hope Index was used to measure hopefulness among PLWS (n = 33) and their caregivers (n = 33) at baseline and immediate post-intervention. Univariable and multivariable regression models were conducted to determine correlates of hopefulness at baseline, while the Actor-Partner Interdependence Model (APIM) was employed to examine the longitudinal, dyadic relationship of hopefulness among and between PLWS and their caregivers.

resultsBetter family functioning was associated with higher levels of hopefulness in PLWS and their caregivers. Lower levels of stigma, lower symptom severity, and lower disability were associated with higher levels of hopefulness in PLWS. For PLWS and their caregivers, actor effects from the APIM model were less than one (PLWS, [Formula: see text]; caregivers, [Formula: see text]), indicating stability (within each person) in hopefulness over time. Regarding partner effects, a caregiver's baseline hopefulness had a positive effect on the hopefulness of their PLWS at follow-up ([Formula: see text]). This indicates that higher caregiver hope at time 0 is associated with higher levels of hope in PLWS at time 1. Baseline hopefulness levels for PLWS had a negative effect on caregivers' hopefulness at follow-up ([Formula: see text]). This suggests that higher hopefulness among PLWS at baseline is associated with lower levels of hope in caregivers at follow-up.

conclusionHopefulness is important to consider in family or caregiver-based treatments for PLWS because caregiver hopefulness may influence improvements in hopefulness among PLWS over time. Future studies should further explore the longitudinal dyadic relationship of hopefulness for these populations, as hope is a non-pharmacological and modifiable mechanism of change that is underutilized in care and treatment plans for PLWS globally.

trial registrationClinical Trials #NCT04013932, July 10, 2019.

Indexed as

CaregiversSchizophreniaHumansQuality of LifeSurveys and QuestionnairesTanzaniaActor-partner interdependence model (APIM)CaregivingHopefulnessPsychotic disordersSchizophrenia

Identifiers

PMID37442999
PMCPMC10339619
OpenAlexW4384133214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.