Evidence map›Paper›PMID 37442966›Full record

Trial reportBMC infectious diseases2023

Prevalence of five treatable sexually transmitted infections among women in Lower River region of The Gambia.

Robert Butcher, Sheikh Jarju, Dolapo Obayemi, Adedapo Olufemi Bashorun, Hristina Vasileva, Hannah Bransbury-Hare, Orighomisan Agboghoroma, Lamin Drammeh, Martin Holland, Emma Harding-Esch and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Robert ButcherClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK. Robert.butcher@lshtm.ac.uk.
Sheikh JarjuMRC Unit The Gambia at London School of Hygiene & Tropical Medicine, London, UK.
Dolapo ObayemiMRC Unit The Gambia at London School of Hygiene & Tropical Medicine, London, UK.
Adedapo Olufemi BashorunMRC Unit The Gambia at London School of Hygiene & Tropical Medicine, London, UK.
Hristina VasilevaClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Hannah Bransbury-HareClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Orighomisan AgboghoromaMRC Unit The Gambia at London School of Hygiene & Tropical Medicine, London, UK.
Lamin DrammehMRC Unit The Gambia at London School of Hygiene & Tropical Medicine, London, UK.
Martin HollandClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Emma Harding-EschClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Ed ClarkeClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.

Funding

Medical Research Council MC_EX_MR/N006070/1Wellcome TrustWellcome Trust 204928/Z/16/ZWellcome Trust MC_EX_MR/N006070/1
6 · The paper itself

Abstract

backgroundThe prevalence of sexually transmitted infections (STIs) in sub-Saharan Africa is poorly described. We aimed to determine the prevalence of five treatable STIs (Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma genitalium, Treponema pallidum) in a sample of Gambian women from the general population.

methodsArchived specimens from 420 women aged 15 - 69 years living in The Gambia enrolled in a clinical trial of human papilloma virus vaccine schedules were tested in this study. Urine samples were tested for C. trachomatis, N. gonorrhoeae, T. vaginalis and M. genitalium using a commercially available, open-platform multiplex PCR kit. A fragment of the ompA gene was amplified from C. trachomatis-positive samples and sequenced. Serum samples were tested for T. pallidum using the Chembio DPP Syphilis Screen and Confirm test.

resultsOverall, 41/420 (9.8%) women tested positive for at least one STI. 32 (7.6%), 9 (2.1%), 1 (0.2%), 1 (0.2%) and 0 (0.0%) tested positive for T. vaginalis, C. trachomatis, N gonorrhoeae, M. genitalium and T. pallidum, respectively. ompA gene sequence was available from five C. trachomatis infections: four were genovar D,one was genovar G and one was genovar F.

conclusionsSTIs are endemic in The Gambia. Monitoring systems should be established.

Indexed as

Chlamydia InfectionsGonorrheaMycoplasma genitaliumMycoplasma InfectionsSexually Transmitted DiseasesAdolescentAdultAgedChlamydia trachomatisFemaleGambiaHumansMiddle AgedNeisseria gonorrhoeaePrevalenceRiversChlamydia trachomatisGambiaMycoplasma genitaliumNeisseria gonorrhoeaePrevalenceSexually transmitted infectionsSyphilisTrichomonas vaginalis

Identifiers

PMID37442966
PMCPMC10347728

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.