Evidence map›Paper›PMID 37442875›Full record

ArticleJournal of bioenergetics and biomembranes2023

Inclusion complex of O-allyl-lawsone with 2-hydroxypropyl-β-cyclodextrin: Preparation, physical characterization, antiparasitic and antifungal activity.

Caroline Deckmann Nicoletti, Raíssa Maria Dos Santos Galvão, Marcella de Sá Haddad Queiroz, Lais Barboclher, Ana Flávia Martins Faria, Guilherme Pegas Teixeira, André Luis Ameida Souza, Fernando de Carvalho da Silva, Vitor Francisco Ferreira, Camilo Henrique da Silva Lima and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of bioenergetics and biomembranes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Caroline Deckmann NicolettiFaculdade de Farmácia, Departamento de Tecnologia Farmacêutica, Universidade Federal Fluminense, 24241-000, Niterói, RJ, Brazil.
Raíssa Maria Dos Santos GalvãoPrograma de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense, Campus Valonguinho, 24020-141, Niterói, RJ, Brasil.
Marcella de Sá Haddad QueirozFaculdade de Farmácia, Departamento de Tecnologia Farmacêutica, Universidade Federal Fluminense, 24241-000, Niterói, RJ, Brazil.
Lais BarboclherFaculdade de Farmácia, Departamento de Tecnologia Farmacêutica, Universidade Federal Fluminense, 24241-000, Niterói, RJ, Brazil.
Ana Flávia Martins FariaPrograma de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense, Campus Valonguinho, 24020-141, Niterói, RJ, Brasil.
Guilherme Pegas TeixeiraLaboratório de Avaliação e Promoção da Saúde Ambiental, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Av. Brasil, n° 4365, Pavilhão Lauro Travassos, sala 01, 21040-900, Manguinhos, Rio de Janeiro, RJ, Brazil.
André Luis Ameida SouzaUniversidade Iguaçu, Nova Iguaçu - RJ, Av. Abílio Augusto Távora, 2134, 26260-045, Jardim Alvorada, Brazil.
Fernando de Carvalho da SilvaDepartamento de Quimica Orgânica, Universidade Federal Fluminense, Campus Valonguinho, 24020-141, Niterói, RJ, Brazil.
Vitor Francisco FerreiraFaculdade de Farmácia, Departamento de Tecnologia Farmacêutica, Universidade Federal Fluminense, 24241-000, Niterói, RJ, Brazil.
Camilo Henrique da Silva LimaInstituto de Química, Universidade Federal do Rio de Janeiro, 21941-909, Rio de Janeiro, RJ, Brazil.
Luana P Borba-SantosInstituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, 21941-170, Rio de Janeiro, RJ, Brazil.
Sonia RozentalInstituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, 21941-170, Rio de Janeiro, RJ, Brazil.
Débora Omena FuturoFaculdade de Farmácia, Departamento de Tecnologia Farmacêutica, Universidade Federal Fluminense, 24241-000, Niterói, RJ, Brazil.
Robson Xavier FariaPrograma de Pós-graduação em Ciências e Biotecnologia, Instituto de Biologia, Universidade Federal Fluminense, Campus Valonguinho, 24020-141, Niterói, RJ, Brasil. robson.xavier@gmail.com.
Universidade Federal Fluminense · BRUniversidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BRUniversidade Iguaçu · BR

Funding

Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
6 · The paper itself

Abstract

The subclass naphthoquinone represents a substance group containing several compounds with important activities against various pathogenic microorganisms. Accordingly, we evaluated O-allyl-lawsone (OAL) antiparasitic and antifungal activity free and encapsulated in 2-hydroxypropyl-β-cyclodextrin (OAL MKN) against Trypanosoma cruzi and Sporothrix spp. OAL and OAL MKN were synthesized and characterized by physicochemical methods. The IC

Indexed as

Chagas DiseaseNaphthoquinonesTrypanosoma cruzi2-Hydroxypropyl-beta-cyclodextrinAnimalsAntifungal AgentsAntiparasitic AgentsMammals2-Hydroxypropyl-beta-cyclodextrinAntifungal AgentsAntiparasitic AgentslawsoneNaphthoquinonesBlood trypomastigoteNaphthoquinonePolysaccharideTopology study

Identifiers

PMID37442875
OpenAlexW4384153531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.