Evidence map›Paper›PMID 37442599›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study.

Patrick Jern, Jinglu Chen, Jouni Tuisku, Tiina Saanijoki, Jussi Hirvonen, Lasse Lukkarinen, Sandra Manninen, Semi Helin, Vesa Putkinen, Lauri Nummenmaa

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Non-Genitally Stimulated Orgasms Increase Plasma Prolactin in a Menopausal Woman.International journal of sexual health : official journal of the World Association for Sexual Health · 2026
    Article
  4. Pleasurable music activates cerebral µ-opioid receptors: a combined PET-fMRI study.European journal of nuclear medicine and molecular imaging · 2025
    Article
  5. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Patrick JernDepartment of Psychology, Åbo Akademi University, Turku, Finland; patrick.jern@abo.fi.
Jinglu ChenTurku PET Centre, University of Turku, Turku, Finland.
Jouni TuiskuTurku PET Centre, University of Turku, Turku, Finland.
Tiina SaanijokiTurku PET Centre, University of Turku, Turku, Finland.
Jussi HirvonenTurku PET Centre, University of Turku, Turku, Finland.
Lasse LukkarinenTurku PET Centre, University of Turku, Turku, Finland.
Sandra ManninenTurku PET Centre, University of Turku, Turku, Finland.
Semi HelinTurku PET Centre, University of Turku, Turku, Finland.
Vesa PutkinenTurku PET Centre, University of Turku, Turku, Finland.
Lauri NummenmaaTurku PET Centre, University of Turku, Turku, Finland.
University of Turku · FIÅbo Akademi University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endogenous μ-opioid receptor (MOR) system plays a key role in the mammalian reward circuit. Human and animal experiments suggest the involvement of MORs in human sexual pleasure, yet this hypothesis currently lacks in vivo support.

Indexed as

Analgesics, OpioidOrgasmBrainHumansMagnetic Resonance ImagingPositron-Emission TomographyAnalgesics, OpioidarousalfMRImanual penile stimulationopioidsorgasmPET

Identifiers

PMID37442599
PMCPMC10394307
OpenAlexW4384273700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.