ArticleThe British journal of surgery2023
Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE.
Article in The British journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 52 citations in OpenAlex.
- Time of Detection of Liver Metastases and Survival in Patients With Colorectal Cancer.JAMA network open · 2026Trial
- Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer.Asia-Pacific journal of clinical oncology · 2026Observational
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- Disappearing Colorectal Liver Metastases: Should the Treatment Sequence Be Reconsidered for Selected Lesions?Cancers · 2026Article
- Resect first in resectable colorectal liver metastases: Recalibrating the default.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Social and Surgical Drivers of Survival in Colorectal Liver Metastases: An NCBD Analysis.Journal of surgical oncology · 2026Article
- Early-Onset Colorectal Cancer With Liver-Only Metastases: A Retrospective Cohort Study Integrating Prospectively Collected Real-World Clinical and Molecular Data From an Australian National Database (2009-2024) to Guide Treatment Planning.The Medical journal of Australia · 2026Article
- Factors Associated with the Timing of Liver Metastasis After Colorectal Cancer Surgery: A Retrospective Multicenter Study.Cancers · 2026Article
- Management Strategies for Disappearing Colorectal Liver Metastases After Systemic Chemotherapy: Long-Term Outcomes and Preoperative Prediction of 'True Complete Response'.Annals of gastroenterological surgery · 2026Article
- Early unresectable relapse after hepatic resection for colorectal liver metastases: a focus on time to surgical failure.Updates in surgery · 2026Article
- Comprehensive management of synchronous colorectal liver metastases at a high-volume center: a propensity score-matched analysis.Updates in surgery · 2025Article
- Preoperative prediction and localization of synchronous metastases in colon cancer: the role of CECT combined with clinical characteristics.BMC cancer · 2025Article
- Tissue-Specific Immunosuppressive and Proliferating Macrophages Fuel Early Metastatic Progression of Human Colorectal Cancer to the Liver.Cancer immunology research · 2025Article
- Effect of disappearing liver metastases during pre-ablation chemotherapy on the prognosis of percutaneous microwave ablation in synchronous colorectal liver metastases patients.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Laparoscopic resection combined with ablation for multiple colorectal liver metastases: a multicentre propensity-matched analysis.Surgical endoscopy · 2025Article
- Oncological safety of portal vein embolization without prior tumour clearance in the future liver remnant followed by one-stage hepatectomy for bilateral colorectal liver metastases.The British journal of surgery · 2025Article
- Consideration of tumor genomics in the management of synchronous colorectal liver metastases.Surgery open science · 2025Article
- Machine learning-based radiomics models for the prediction of metachronous liver metastases in patients with colorectal cancer: A multimodal study.Oncology letters · 2025Article
- Dynamic Prognostic Models for Colorectal Cancer With Liver Metastases.JAMA network open · 2025Article
- Prognostic Factors in Colorectal Liver Metastases: An Exhaustive Review of the Literature and Future Prospectives.Cancers · 2025Review
Corrections and comments
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Authors and funding
39 authors at 20 institutions in 14 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim of this project was to provide a practical framework for care of patients with synchronous colorectal cancer and liver metastases, with a focus on terminology, diagnosis, and management.
methodsThis project was a multiorganizational, multidisciplinary consensus. The consensus group produced statements which focused on terminology, diagnosis, and management. Statements were refined during an online Delphi process, and those with 70 per cent agreement or above were reviewed at a final meeting. Iterations of the report were shared by electronic mail to arrive at a final agreed document comprising 12 key statements.
resultsSynchronous liver metastases are those detected at the time of presentation of the primary tumour. The term 'early metachronous metastases' applies to those absent at presentation but detected within 12 months of diagnosis of the primary tumour, the term 'late metachronous metastases' applies to those detected after 12 months. 'Disappearing metastases' applies to lesions that are no longer detectable on MRI after systemic chemotherapy. Guidance was provided on the recommended composition of tumour boards, and clinical assessment in emergency and elective settings. The consensus focused on treatment pathways, including systemic chemotherapy, synchronous surgery, and the staged approach with either colorectal or liver-directed surgery as first step. Management of pulmonary metastases and the role of minimally invasive surgery was discussed.
conclusionThe recommendations of this contemporary consensus provide information of practical value to clinicians managing patients with synchronous colorectal cancer and liver metastases.
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