Observational studyThe journal of pain2023
The Natural History of Knee Osteoarthritis Pain Experience and Risk Profiles.
Observational study in The journal of pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 11 citations in OpenAlex.
- Studying the Natural History of the Knee Joint.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Review
- Effects of thrombospondin-1 (THBS1) and toll-like receptor 4 (TLR-4) levels in the serum and synovial fluid of patients with knee osteoarthritis.Journal of medical biochemistry · 2026Article
- The Thai ICOAP-Hip: Cross-Cultural Adaptation and Validation for Assessing Intermittent and Constant Pain in Hip Osteoarthritis.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- A retrospective predictive model for worsening knee osteoarthritis pain by integrating baseline gait biomechanics and wearable gait parameters.American journal of translational research · 2026Article
- Association between constant and intermittent knee pain and T2 values and cartilage thickness: data from the osteoarthritis initiative.Arthritis research & therapy · 2025Article
- Temporal Associations of Physical Activity With Subsequent Knee Pain in Individuals With Knee Osteoarthritis: An Ecological Momentary Assessment Study.European journal of pain (London, England) · 2025Article
- Association between widespread pain and psychosocial factors in people with knee osteoarthritis: a cross-sectional study of patients from primary care in Denmark.Physiotherapy theory and practice · 2025Article
- Spatiotemperal Dynamics of Osteoarthritis: Bridging Insights from Bench to Bedside.Aging and disease · 2024Review
- Measurement of Pain Frequency Associated With Knee Osteoarthritis: Future Directions.The journal of pain · 2024Article
- Significance of radiographic temporomandibular degenerative joint disease findings.Seminars in orthodontics · 2024Article
- Unveiling MRI-based structural phenotypes in temporomandibular joint osteoarthritis: implications for clinical practice and research.Dental press journal of orthodontics · 2024Article
- Ecological momentary assessment for symptom monitoring among people with knee osteoarthritis: A scoping review.Digital healthReview
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The study aimed to characterize the natural history of the pain experience, concurrently considering intermittent and constant pain over 4 years, and determine baseline factors associated with unfavorable trajectories in individuals with chronic knee pain. The Osteoarthritis Initiative (OAI) is a prospective, observational study of people with or at higher risk for knee osteoarthritis. The Intermittent and Constant Osteoarthritis Pain (ICOAP) was assessed annually at 48-to-96-month OAI visits. Twenty-eight baseline sociodemographic, knee-specific, and health-related characteristics were assessed. Group-based dual-trajectory modeling identified pain experience patterns indicated by ICOAP intermittent and constant pain scores over 4 years. Multivariable multinomial logistic regression models determined baseline factors associated with membership in each dual-trajectory group. Four longitudinal pain experience patterns were identified (n = 3,584, mean age = 64.8 [standard deviation 9.0] years, BMI = 28.6 [5.0] kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.