Evidence map›Paper›PMID 37442282›Full record

ArticleToxicology letters2023

Acute inhalation of tungsten particles results in early signs of cardiac injury.

Sage Templeton, Charlotte M McVeigh, Colin Nguyen, Russell Hunter, David Scieszka, Guy W Herbert, Edward B Barr, Rui Liu, Haiwei Gu, Barry E Bleske and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Toxicology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sage TempletonThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Charlotte M McVeighThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Colin NguyenThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Russell HunterThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
David ScieszkaThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Guy W HerbertThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Edward B BarrThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Rui LiuThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Haiwei GuCenter for Translational Science, Florida International University, Port St. Lucie, FL 34987, USA.
Barry E BleskeThe University of New Mexico College of Pharmacy, Department of Pharmacy Practice and Administrative Sciences, Albuquerque, NM 87131, USA.
Matthew J CampenThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA.
Alicia M BoltThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, USA. Electronic address: ambolt@salud.unm.edu.
University of New Mexico · USFlorida International University · US

Funding

University of New Mexico Center for Metals in Biology and Medicine - equipment supplementP20GM130422 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Sebastian Medina · 2020 to 2026
$20.4M
Mechanisms of Vascular Toxicity from Inhaled ToxicantsR01ES014639 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J · 2008 to 2023
$6.7M
Pilot Project CoreP30ES032755 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI FENG, CHANGJIAN (JIM) · 2022 to 2025
$5.2M
Inhalation of Contaminated Mine Waste Dusts as a Route for Systemic Metal ToxicityR01ES026673 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Matthew J Campen, Shahani Noor · 2016 to 2026
$4.8M
Enhancement of Coronary Constriction by Volatile Organic Air ToxicsR56ES014639 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J · 2013 to 2013
$148k
NIEHS NIH HHS P30 ES032755NIEHS NIH HHS R01 ES014639NIEHS NIH HHS R01 ES026673NIEHS NIH HHS R56 ES014639NIGMS NIH HHS P20 GM130422
6 · The paper itself

Abstract

Epidemiological studies have established that exposure to tungsten increases the risk of developing cardiovascular diseases. However, no studies have investigated how tungsten affects cardiac function or the development of cardiovascular disease. Inhalation of tungsten particulates is relevant in occupational settings, and inhalation of particulate matter has a known causative role in driving cardiovascular disease. This study examined if acute inhalation to tungsten particulates affects cardiac function and leads to heart tissue alterations. Female BALB/c mice were exposed to Filtered Air or 1.5 ± 0.23 mg/m

Indexed as

Cardiovascular DiseasesPneumoniaAnimalsFemaleInhalation ExposureLungMiceParticulate MatterTungstenParticulate MatterTungstenCardiovascular DiseaseFibrosisInflammationInhalationReactive Oxygen SpeciesTungsten

Identifiers

PMID37442282
PMCPMC10528412
OpenAlexW4383879171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.