Evidence map›Paper›PMID 37441924›Full record

ArticleJournal of inorganic biochemistry2023

Calorimetric analysis of AdcR and its interactions with zinc(II) and DNA.

Alexander J Cutright, Thualfeqar Al Mohanna, Erin L Matthews, James M Aulds, Justin A Thornton, Sean L Stokes, Joseph P Emerson

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexander J CutrightDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States.
Thualfeqar Al MohannaDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States.
Erin L MatthewsDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States.
James M AuldsDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States.
Justin A ThorntonDepartment of Biological Sciences, Mississippi State University, Mississippi State, MS 39762, United States.
Sean L StokesDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States.
Joseph P EmersonDepartment of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States. Electronic address: jemerson@chemistry.msstate.edu.
Mississippi State University · US

Funding

Zinc dependent conformational changes in AdcR and their impact on DNA bindingP20GM103646 · NIGMS · MISSISSIPPI STATE UNIVERSITY · PI THIBAUDEAU, GISELLE · 2013 to 2022
$21.1M
NIGMS NIH HHS P20 GM103646
6 · The paper itself

Abstract

Zinc(II) ions play critical roles in all known life as structurally important stabilizing ions in proteins, catalytically active metals in enzymes, and signaling agents impacting physiological changes. To maintain homeostasis, the intracellular concentration of zinc(II) is strictly controlled by a family of metal-regulatory proteins in both prokaryotic and eukaryotic organisms. In S. pneumoniae, there are two proteins that share responsibility for Zn

Indexed as

DNAZincAdhesins, BacterialCalorimetry, Differential ScanningProtein BindingStreptococcus pneumoniaeThermodynamicsAdhesins, BacterialDNAZincDifferential scanning calorimetryEnthalpyMetal bindingThermodynamicsTranscription factor

Identifiers

PMID37441924
PMCPMC12684291
OpenAlexW4383215825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.