Evidence map›Paper›PMID 37441686›Full record

ArticleFrontiers in medicine2023

The role and safety of UVA and UVB in UV-induced skin erythema.

Jing-Wen Yang, Guo-Biao Fan, Fei Tan, Hai-Mei Kong, Qing Liu, Ying Zou, Yi-Mei Tan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Design rules for externally triggered drug uncaging under optical and radiolytic regimes.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2026
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  3. Anti-Photoaging Effects of a Standardized Hot Water Extract ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jing-Wen Yang *Department of Skin and Cosmetics Research, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Guo-Biao Fan *Department China Regulatory Affairs, LVMH Perfume and Cosmetic (Shanghai) Limited Company, Shanghai, China.
Fei TanDepartment of Skin and Cosmetics Research, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Hai-Mei KongDepartment of Skin and Cosmetics Research, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Qing LiuDepartment China Regulatory Affairs, LVMH Perfume and Cosmetic (Shanghai) Limited Company, Shanghai, China.
Ying ZouDepartment of Skin and Cosmetics Research, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Yi-Mei TanDepartment of Skin and Cosmetics Research, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Shanghai Skin Disease Hospital · CNTongji University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Different wavelengths of ultraviolet (UV) light cause skin damage through different mechanisms. Minimal erythema dose (MED) is usually used to clinically evaluate skin sensitivity to ultraviolet radiation by inducing skin erythema using ultraviolet B (UVB) or ultraviolet A (UVA) + UVB. Aims: In this study, we detected changes in the blood flow at the MED erythema caused by UVB and UVA + UVB radiation through optical coherence tomography (OCT) to explain the role of different bands of ultraviolet rays in erythema induction. Methods: Two MED irradiation areas on the subjects' back were irradiated with UVB alone or UVA + UVB (UVA: UVB = 8:1). The absolute energy of UVB remained the same in UVB and UVA+UVB. At 24 h after the irradiation, the changes in the blood flow in the MED area were detected using OCT. Results: Compared with the blank control, the maximum blood flow depth, blood flow peak, and total blood flow of UVB-MED and UVA+UVB-MED were significantly increased. Notably, the maximum blood flow depth and blood flow peak of UVB-MED were higher than UVA+UVB-MED. There was no significant difference in total blood perfusion between UVA+UVB-MED and UVB-MED. Under the same UVB energy, the skin erythema caused by UVA + UVB was weaker than UVB alone. Conclusions: The analysis of local blood flow by OCT showed that the peak and maximum depth of local blood flow caused by UVB alone were significantly higher than UVA + UVB.

Indexed as

maximum blood flow depthminimal erythema doseoptical coherence tomographyoptical coherence tomography UVAtotal blood flowUVAUVB

Identifiers

PMID37441686
PMCPMC10335810
OpenAlexW4382242911

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.