Evidence map›Paper›PMID 37441542›Full record

ArticleClinical and translational radiation oncology2023

Patterns of locoregional recurrences and suggestion of the clinical target volume in resected perihilar extrahepatic cholangiocarcinoma.

Younghee Park, Wonguen Jung, Kyubo Kim, Ah Ram Chang, Hae Jin Park, Hyeon Kang Koh, Byoung Hyuck Kim

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Younghee ParkDepartment of Radiation Oncology, Ewha Womans University College of Medicine, Seoul, South Korea.
Wonguen JungDepartment of Radiation Oncology, Ewha Womans University College of Medicine, Seoul, South Korea.
Kyubo KimDepartment of Radiation Oncology, Ewha Womans University College of Medicine, Seoul, South Korea.
Ah Ram ChangDepartment of Radiation Oncology, Soonchunhyang University College of Medicine, Seoul, South Korea.
Hae Jin ParkDepartment of Radiation Oncology, Hanyang University College of Medicine, Seoul, South Korea.
Hyeon Kang KohDepartment of Radiation Oncology, Konkuk University School of Medicine, Seoul, South Korea.
Byoung Hyuck KimDepartment of Radiation Oncology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, South Korea.
Ewha Womans University · KRHanyang University · KRKonkuk University · KRSeoul National University · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the patterns of locoregional recurrence (LRR) in patients with perihilar extrahepatic cholangiocarcinoma (PEHC) treated with radical resection and to suggest the optimal target volume for elective nodal irradiation. Methods: Medical records of PEHC patients who underwent radical resection between January 2000 and September 2021 at five institutions were reviewed. Patients who were confirmed with LRR in the follow-up imaging study were included. The LRR sites were mapped onto the corresponding sites in template computed tomography images. The margin around the vascular structure was investigated to generate the clinical target volume (CTV) covering the common sites of regional recurrences. Results: A total of 87 LRRs in 46 patients were identified, 29 (33.3%) of which were local recurrences and 58 (66.7%) were regional recurrences. The most common site of local recurrence was the liver resection margin ( Conclusions: The LRR patterns in the resected PEHC were evaluated and specific guidelines for nodal CTV delineation were provided, which may help physicians delineating the target volume in postoperative radiotherapy for PEHC. These findings need further validation in a lager cohort.

Indexed as

Clinical target volumeLocoregional recurrencePerihilar extrahepatic cholangiocarcinomaRadiotherapy

Identifiers

PMID37441542
PMCPMC10334123
OpenAlexW4379467392

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.