Evidence map›Paper›PMID 37441463›Full record

ReviewMedComm2023

Nanopore sequencing technology and its applications.

Peijie Zheng, Chuntao Zhou, Yuemin Ding, Bin Liu, Liuyi Lu, Feng Zhu, Shiwei Duan

Abstract readReview
In one paragraph

Review in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Emerging roles of mJournal of assisted reproduction and genetics · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Genomic insights intoMicrobiology spectrum · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
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  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peijie ZhengDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.
Chuntao ZhouDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.
Yuemin DingDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.ORCID https://orcid.org/0000-0003-0547-5358
Bin LiuDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.ORCID https://orcid.org/0000-0002-8982-8925
Liuyi LuDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.
Feng ZhuDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.
Shiwei DuanDepartment of Clinical Medicine School of Medicine Zhejiang University City College Hangzhou China.ORCID https://orcid.org/0000-0001-7682-2877

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the development of Sanger sequencing in 1977, sequencing technology has played a pivotal role in molecular biology research by enabling the interpretation of biological genetic codes. Today, nanopore sequencing is one of the leading third-generation sequencing technologies. With its long reads, portability, and low cost, nanopore sequencing is widely used in various scientific fields including epidemic prevention and control, disease diagnosis, and animal and plant breeding. Despite initial concerns about high error rates, continuous innovation in sequencing platforms and algorithm analysis technology has effectively addressed its accuracy. During the coronavirus disease (COVID-19) pandemic, nanopore sequencing played a critical role in detecting the severe acute respiratory syndrome coronavirus-2 virus genome and containing the pandemic. However, a lack of understanding of this technology may limit its popularization and application. Nanopore sequencing is poised to become the mainstream choice for preventing and controlling COVID-19 and future epidemics while creating value in other fields such as oncology and botany. This work introduces the contributions of nanopore sequencing during the COVID-19 pandemic to promote public understanding and its use in emerging outbreaks worldwide. We discuss its application in microbial detection, cancer genomes, and plant genomes and summarize strategies to improve its accuracy.

Indexed as

cancerCOVID‐19genomemutationnanopore sequencingpandemicplantSARS‐CoV‐2

Identifiers

PMID37441463
PMCPMC10333861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.