Evidence map›Paper›PMID 37441441›Full record

ArticleAmerican journal of clinical and experimental urology2023

Proteomics analysis of urine and catheter-associated biofilms in spinal cord injury patients.

Fernando J Garcia-Marques, Elissa Zakrasek, Abel Bermudez, Alexandra L Polasko, Shiqin Liu, Tanya Stoyanova, James D Brooks, John Lavelle, Sharon J Pitteri

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of clinical and experimental urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Fernando J Garcia-MarquesCanary Center at Stanford for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine Palo Alto, CA 94304, USA.
Elissa ZakrasekVeterans Affairs Palo Alto Health Care System Palo Alto, CA 94304, USA.
Abel BermudezCanary Center at Stanford for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine Palo Alto, CA 94304, USA.
Alexandra L PolaskoDepartment of Urology, Stanford University School of Medicine Stanford, CA 94305-5118, USA.
Shiqin LiuCanary Center at Stanford for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine Palo Alto, CA 94304, USA.
Tanya StoyanovaCanary Center at Stanford for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine Palo Alto, CA 94304, USA.
James D BrooksCanary Center at Stanford for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine Palo Alto, CA 94304, USA.
John LavelleVeterans Affairs Palo Alto Health Care System Palo Alto, CA 94304, USA.
Sharon J PitteriCanary Center at Stanford for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine Palo Alto, CA 94304, USA.
Stanford University · USStanford Medicine · USVA Palo Alto Health Care System · US

Funding

Stanford O'Brien Urology Research CenterU54DK130065 · NIDDK · STANFORD UNIVERSITY · PI JAMES D. BROOKS · 2021 to 2026
$8.3M
NIDDK NIH HHS U54 DK130065
6 · The paper itself

Abstract

After spinal cord injury (SCI), use chronic urinary catheters for bladder management is common, making these patients especially vulnerable to catheter-associated complications. Chronic catheterization is associated with bacterial colonization and frequent catheter-associated urinary tract infections (CAUTI). One determinant of infection success and treatment resistance is production of catheter-associated biofilms, composed of microorganisms and host- and microbial-derived components. To better understand the biofilm microenvironment, we performed proteomics analysis of catheter-associated biofilms and paired urine samples from four people with SCI with chronic indwelling urinary catheters. We developed a novel method for the removal of adhered cellular components on catheters that contained both human and microbial homologous proteins. Proteins from seven microbial species were identified including:

Indexed as

biofilmCathetermicrobial proteinsproteomicsspinal cord injuryurine

Identifiers

PMID37441441
PMCPMC10333135
OpenAlexW4384277360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.