Evidence map›Paper›PMID 37441378›Full record

ReviewHeliyon2023

Babesiosis: Current status and future perspectives in Pakistan and chemotherapy used in livestock and pet animals.

Muhammad Azhar, Javaid Ali Gadahi, Bachal Bhutto, Sambreena Tunio, Waseem Ali Vistro, Haleema Tunio, Sahar Bhutto, Teerath Ram

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Molecular epidemiology and risk factors associated withJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2026
    Article
  3. Tafenoquine: A Breakthrough Option for Babesiosis Treatment.Tropical medicine and infectious disease · 2026
    Article
  4. SynergisticFrontiers in veterinary science · 2026
    Article
  5. Article
  6. Article
  7. A review of Babesiosis caused by Babesia ovis in small ruminants.Tropical animal health and production · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Muhammad AzharDepartment of Veterinary Parasitology, Sindh Agriculture University, Tandojam, Pakistan.
Javaid Ali GadahiDepartment of Veterinary Parasitology, Sindh Agriculture University, Tandojam, Pakistan.
Bachal BhuttoDepartment of Veterinary Parasitology, Sindh Agriculture University, Tandojam, Pakistan.
Sambreena TunioDepartment of Animal Product Technology, Sindh Agriculture University, Tandojam, Pakistan.
Waseem Ali VistroDepartment of Veterinary Anatomy, Sindh Agriculture University, Tandojam, Pakistan.
Haleema TunioDepartment of Poultry Husbandry, Sindh Agriculture University, Tandojam, Pakistan.
Sahar BhuttoDepartment of Veterinary Pathology, Sindh Agriculture University, Tandojam, Pakistan.
Teerath RamDepartment of Animal Nutrition, Sindh Agriculture University, Tandojam, Pakistan.
Sindh Agriculture University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Babesiosis is a protozoal disease affect livestock and pet animals such as cattle, buffaloes, sheep, goats, horses, donkeys, mules, dogs, and cats. It causes severe economic losses in livestock as well as in pet animals. A large number of dairy animals are imported in order to fulfill the demands of milk, milk, meat and its products. In addition, different pet animals are transported from Pakistan to various parts of the world, therefore, it is important to identify the current status and distribution of babesiosis throughout Pakistan in order to control the disease and draw attention for future research, diagnosis, treatment and control of this diseases. No work has been done on a complete review on up-to-date on blood protozoal disease burden in Pakistan. This article will provide about the complete background of babesiosis in ruminants, equines and pet animals, its current status, distribution, vectors in Pakistan and allopathic and ethnoveterinary treatments used against babesiosis. Babesiosis may be subclinical (apparently normal) and may be clinical with acute to chronic disease and sometimes fatal. Babesia is found and develops inside the erythrocytes (red blood cells). Clinically, it causes fever, fatigue, lethargy, pallor mucus membranes, malaise, cachexia, respiratory distress, jaundice, icterus, hemolytic anemia, hemoglobinuria, lymphadenopathy, chollangocytitis, hepatomegaly, and splenomegaly. Chemotherapy for babesiosis includes Imidocarb dipropionate, Diaminazine aceturate Atovaquone and Bupravaquone, Azithromycin, Quinuronium sulfate and Amicarbalidesio-thionate are most widely used. Supportive therapy includes multivitamins, fluid therapy, antipyretics intravenous fluids, and blood transfusions are used if necessary. In addition, there are certain ethnoveterinary (homeopathic) ingredients which having anti-babesial activity. As the resistance against these drugs is developing every day. New more specific long-lasting drugs should be developed for the treatment of Babesiosis. Further studies should be done on disease genome of different species of

Indexed as

BabesiosisChemotherapyPakistanVeterinary medicine

Identifiers

PMID37441378
PMCPMC10333442
OpenAlexW4381112578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.