Evidence map›Paper›PMID 37441062›Full record

ReviewInternational journal of veterinary science and medicine2023

Interspecies transmission of SARS CoV-2 with special emphasis on viral mutations and ACE-2 receptor homology roles.

Mervat E Hamdy, Ayman H El Deeb, Naglaa M Hagag, Momtaz A Shahein, Osama Alaidi, Hussein A Hussein

Open access · goldAbstract readReview
In one paragraph

Review in International journal of veterinary science and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mervat E HamdyGenome Research Unit, Animal Health Research Institute, Agriculture Research Centre, Giza, Egypt.ORCID https://orcid.org/0000-0002-7824-4051
Ayman H El DeebDepartment of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Naglaa M HagagGenome Research Unit, Animal Health Research Institute, Agriculture Research Centre, Giza, Egypt.
Momtaz A ShaheinDepartment of Virology, Animal Health Research Institute, Agriculture Research Centre, Giza, Egypt.
Osama AlaidiBiocomplexity for Research and Consulting Co., Cairo, Egypt.
Hussein A HusseinDepartment of Virology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Agricultural Genetic Engineering Research Institute · EGCairo University · EGSt. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 outbreak was first reported in 2019, Wuhan, China. The spillover of the disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), to a wide range of pet, zoo, wild, and farm animals has emphasized potential zoonotic and reverse zoonotic viral transmission. Furthermore, it has evoked inquiries about susceptibility of different animal species to SARS-CoV-2 infection and role of these animals as viral reservoirs. Therefore, studying susceptible and non-susceptible hosts for SARS-CoV-2 infection could give a better understanding for the virus and will help in preventing further outbreaks. Here, we review structural aspects of SARS-CoV-2 spike protein, the effect of the different mutations observed in the spike protein, and the impact of ACE2 receptor variations in different animal hosts on inter-species transmission. Moreover, the SARS-CoV-2 spillover chain was reviewed. Combination of SARS-CoV-2 high mutation rate and homology of cellular ACE2 receptors enable the virus to transcend species barriers and facilitate its transmission between humans and animals.

Indexed as

and ACE2mutationsSARS-CoV-2spikespillover

Identifiers

PMID37441062
PMCPMC10334861
OpenAlexW4383750243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.