Evidence map›Paper›PMID 37440972›Full record

ArticleSAGE open medical case reports2023

Nicolau syndrome associated with fluphenazine depot: A case report.

Soumitra Das, Vallabh Shet, Thusanth Jogarajah, Abdulgafar Ibrahim, Marlon Reyes, Elaiza Marie Fernandez Co, Balaswamy Reddy

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Soumitra DasThe Royal Melbourne Hospital, Parkville, VIC, Australia.
Vallabh ShetBangalore Medical College & Research Institute, Bangalore, India.
Thusanth JogarajahFaculty of Medicine, Richmond Gabriel University, Belair, Saint Vincent and the Grenadines.ORCID https://orcid.org/0000-0002-1850-064X
Abdulgafar IbrahimInstitute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
Marlon ReyesAmerican University of Antigua College of Medicine, St. John's, Antigua and Barbuda.
Elaiza Marie Fernandez CoCebu Institute of Medicine, Cebu City, Philippines.
Balaswamy ReddyDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
American University of Antigua · AGBangalore Medical College and Research Institute · INGeorgia State University · USNational Institute of Mental Health and Neurosciences · INThe Royal Melbourne Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicolau syndrome is a rare condition characterized by severe pain at the site of injection, leading to ulceration and necrosis of the local tissues. Its presentation is usually acute. Nicolau syndrome is commonly seen in patients after intramuscular, intra-articular, or subcutaneous injections of non-steroidal anti-inflammatory drugs, antiepileptics, antipsychotics, antibiotics, antihistamines, and corticosteroids. Immediate diagnosis and management of this syndrome are of great importance. We herein report a rare presentation of Nicolau syndrome in a 36-year-old married male who suffered from paranoid schizophrenia for the past 3 years. The patient presented with dull pain, mild swelling, and necrotic ulceration over the injection site after receiving intramuscular fluphenazine. The patient underwent wound debridement and was given prophylactic antibiotics. Despite a wide range of therapeutic options for the management of Nicolau syndrome described in the literature, there exist limited guidelines for its management.

Indexed as

adverse reactionCase reportdepot antipsychoticsfluphenazineinjection site ulcerationNicolau syndrome

Identifiers

PMID37440972
PMCPMC10333627
OpenAlexW4382792042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.