Evidence map›Paper›PMID 37440965›Full record

ArticleJournal of the Endocrine Society2023

Pregnancy-associated Steroid Effects on Insulin Sensitivity, Adipogenesis, and Lipogenesis: Role of Wnt/β-Catenin Pathway.

Neethu Sara Alex, Habibur Rahaman Khan, Subbaraya Gudde Ramachandra, Rudraiah Medhamurthy

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Decreased RSPO3 and β-Catenin in Preeclampsia: Correlation with Blood Pressure and Pregnancy Outcomes.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Neethu Sara AlexDepartment of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.ORCID https://orcid.org/0000-0002-2228-7618
Habibur Rahaman KhanDepartment of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.
Subbaraya Gudde RamachandraDepartment of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.
Rudraiah MedhamurthyDepartment of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.ORCID https://orcid.org/0000-0003-2731-9954
Indian Institute of Science Bangalore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: The shift in maternal energy metabolism characteristic of pregnancy is thought to be driven by various hormonal changes, especially of ovarian and placental steroids. Imbalances in circulating estradiol (E Objective: Our study was aimed at elucidating the metabolic function of the steroids E Methods: The ovariectomized (OVX) rat was used as a model system to study the effect of known concentrations of exogenously administered E Results: In the present study, we observed that E Conclusion: The findings presented in this study highlight the role of steroids and Wnt pathway in glucose and lipid metabolism and are relevant to understanding the pathophysiology of metabolic disorders arising from hormonal disturbances.

Indexed as

adipose tissueestradiolinsulin signalinglipid metabolismprogesteroneskeletal muscle

Identifiers

PMID37440965
PMCPMC10334487
OpenAlexW4379742642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.