Evidence map›Paper›PMID 37440950›Full record

ReviewJournal of clinical and experimental hepatology

Guideline Review: European Association for the Study of Liver (EASL) Clinical Practice Guidelines on Haemochromatosis.

James Liu Yin, Christopher Cussen, Christopher Harrington, Pierre Foskett, Kishor Raja, Aftab Ala

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

James Liu YinInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
Christopher CussenDepartment of Gastroenterology and Hepatology, Royal Surrey NHS Foundation Trust, Guildford, UK.
Christopher HarringtonSAS Trace Element Laboratory, Royal Surrey NHS Foundation Trust, Guildford, UK.
Pierre FoskettBerkshire and Surrey Pathology Services, Royal Surrey NHS Foundation Trust, Guildford, UK.
Kishor RajaDepartment of Biochemistry, Synnovis Analytics, King's College Hospital NHS Foundation Trust, London, UK.
Aftab AlaInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
Royal Surrey NHS Foundation Trust · GBKing's College Hospital NHS Foundation Trust · GBUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Association for the Study of the Liver (EASL) has recently (June 2022) produced new clinical practice guidelines for the investigation and management of haemochromatosis, to replace the previous document published in 2010. Here, we provide an overview of the principal changes recommended for the investigation and management of haemochromatosis arising from these guidelines and highlight particular areas where evidence is lacking and where future focus on specific research would improve patient treatment and outcomes. The guideline provides several important new recommendations that will have a meaningful impact on patient management. Specifically, the use of hepatic elastography as a non-invasive assessment of fibrosis, erythrocytapheresis as an alternative treatment modality to classical phlebotomy, surveillance for hepatocellular carcinoma, dietary recommendations in patients with haemochromatosis and guidance on controversial topics including the management of

Indexed as

EASLguideline reviewhaemochromatosisliver disease

Identifiers

PMID37440950
PMCPMC10333946
OpenAlexW4308806140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.