Evidence map›Paper›PMID 37440917›Full record

ArticleFrontiers in neuroscience2023

Single-cell chromatin accessibility profiling of cell-state-specific gene regulatory programs during mouse organogenesis.

Qiuting Deng, Shengpeng Wang, Zijie Huang, Qing Lan, Guangyao Lai, Jiangshan Xu, Yue Yuan, Chang Liu, Xiumei Lin, Weimin Feng and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Qiuting DengCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Shengpeng WangCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Zijie HuangCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Qing LanBGI-Shenzhen, Shenzhen, China.
Guangyao LaiBGI-Shenzhen, Shenzhen, China.
Jiangshan XuBGI-Hangzhou, Hangzhou, China.
Yue YuanBGI-Hangzhou, Hangzhou, China.
Chang LiuBGI-Hangzhou, Hangzhou, China.
Xiumei LinCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Weimin FengCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Wen MaBGI-Shenzhen, Shenzhen, China.
Mengnan ChengBGI-Hangzhou, Hangzhou, China.
Shijie HaoCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Shanshan DuanCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Huiwen ZhengBGI-Hangzhou, Hangzhou, China.
Xiaoyan ChenBGI-Hangzhou, Hangzhou, China.
Yong HouCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Yingjie LuoBGI-Shenzhen, Shenzhen, China.
Longqi LiuCollege of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
Chuanyu LiuBGI-Shenzhen, Shenzhen, China.
BGI Group (China) · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammals, early organogenesis begins soon after gastrulation, accompanied by specification of various type of progenitor/precusor cells. In order to reveal dynamic chromatin landscape of precursor cells and decipher the underlying molecular mechanism driving early mouse organogenesis, we performed single-cell ATAC-seq of E8.5-E10.5 mouse embryos. We profiled a total of 101,599 single cells and identified 41 specific cell types at these stages. Besides, by performing integrated analysis of scATAC-seq and public scRNA-seq data, we identified the critical

Indexed as

cis-regulatory elementsmouse organogenesisparaxial mesodermsingle-cell ATAC-seqspinal cord

Identifiers

PMID37440917
PMCPMC10333525
OpenAlexW4382281163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.