Evidence map›Paper›PMID 37440432›Full record

ArticleeLife2023

Importance of glutamine in synaptic vesicles revealed by functional studies of

Xiaobo Jia, Jiemin Zhu, Xiling Bian, Sulin Liu, Sihan Yu, Wenjun Liang, Lifen Jiang, Renbo Mao, Wenxia Zhang, Yi Rao

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. ACE2: Friend or Foe in Post-COVID-19 Neurodegeneration?International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Computational and structural biotechnology journal · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Xiaobo Jia *Chinese Institute for Brain Research, Beijing, China.ORCID 0000-0002-4214-8906
Jiemin Zhu *Laboratory of Neurochemical Biology, PKU-IDG/McGovern Institute for Brain Research, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, Peking University, Beijing, China.
Xiling Bian *Laboratory of Neurochemical Biology, PKU-IDG/McGovern Institute for Brain Research, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, Peking University, Beijing, China.
Sulin LiuChangping Laboratory, Beijing, China.ORCID 0000-0002-6776-2216
Sihan YuChinese Institute for Brain Research, Beijing, China.
Wenjun LiangChangping Laboratory, Beijing, China.
Lifen JiangInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, China.
Renbo MaoChinese Institute for Brain Research, Beijing, China.
Wenxia ZhangLaboratory of Neurochemical Biology, PKU-IDG/McGovern Institute for Brain Research, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, Peking University, Beijing, China.
Yi RaoChinese Institute for Brain Research, Beijing, China.ORCID 0000-0002-0405-5426
McGovern Institute for Brain Research · USAcademy of Medical Sciences · GB

Funding

Chinese Academy of Medical Sciences Initiative for Innovative Medicine 2019-I2M-5-015
6 · The paper itself

Abstract

Human mutations in the gene encoding the solute carrier (SLC) 6A17 caused intellectual disability (ID). The physiological role of

Indexed as

Intellectual DisabilitySynaptic VesiclesAnimalsGlutamineMiceMutationProteomicsGlutamineglutaminelearningmemorymouseneuroscienceSLC6A17synaptic vesicle

Identifiers

PMID37440432
PMCPMC10393021
OpenAlexW4362617722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.