Evidence map›Paper›PMID 37440120›Full record

ArticleMolecular and cellular biochemistry2024

Y-chromosome in the olfactory neuroepithelium as a potential biomarker of depression in women with male offspring: an exploratory study.

Pilar Álvarez, Beatriz Bellosillo, Francesc Colom, Raquel Longarón, Marta Barrera-Conde, Lierni Fernández-Ibarrondo, Alba Toll, José María Ginés, Rafael de la Torre, Víctor Pérez-Solá and 1 more

Abstract read
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In one paragraph

Article in Molecular and cellular biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Presence of fetal microchimerisms in the heart and effect on cardiac repair.Frontiers in cell and developmental biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pilar ÁlvarezMental Health Research Group, Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain. palvarezl@psmar.cat.
Beatriz BellosilloGroup of Applied Clinical Research in Haematology, Cancer Research Program-IMIM (Hospital del Mar Medical Research Institute), 08003, Barcelona, Spain.
Francesc ColomMental Health Research Group, Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.
Raquel LongarónGroup of Applied Clinical Research in Haematology, Cancer Research Program-IMIM (Hospital del Mar Medical Research Institute), 08003, Barcelona, Spain.
Marta Barrera-CondeDepartment of Medicine and Life Sciences, Pompeu Fabra University, 08003, Barcelona, Spain.
Lierni Fernández-IbarrondoGroup of Applied Clinical Research in Haematology, Cancer Research Program-IMIM (Hospital del Mar Medical Research Institute), 08003, Barcelona, Spain.
Alba TollMental Health Research Group, Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.
José María GinésMAR Health Park Consortium, 08003, Barcelona, Spain.
Rafael de la TorreDepartment of Medicine and Life Sciences, Pompeu Fabra University, 08003, Barcelona, Spain.
Víctor Pérez-SoláMental Health Research Group, Hospital del Mar Medical Research Institute (IMIM), 08003, Barcelona, Spain.
Patricia RobledoDepartment of Medicine and Life Sciences, Pompeu Fabra University, 08003, Barcelona, Spain.

Funding

Instituto de Salud Carlos III PI15/0039
6 · The paper itself

Abstract

The persistence of fetal cells in the mother (fetal microchimerism (FMc)) has been described in maternal tissues essential to the newborn. FMc is associated with several diseases that start or worsen in pregnancy or postpartum. This exploratory study reports-for the first time-the presence of FMc in the olfactory neuroepithelium (ON) of both healthy and depressed women with male offspring. However, depressed women had fewer microchimeric cells (digital PCR). The existence of FMc in the ON could facilitate mother-child bonding. These findings open new pathways to study FMc in the ON, female depression, and mother-child bonding.

Indexed as

Chromosomes, Human, YDepressionAdultBiomarkersFemaleHumansMaleOlfactory MucosaPregnancyBiomarkersBondingFetal microchimerismMajor depressive disorderOlfactory neuroepithelium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.