Evidence map›Paper›PMID 37440087›Full record

ReviewAdvances in experimental medicine and biology2023

Primary Retinal Cell Cultures as a Model to Study Retina Biology.

Germán A Michelis, Luis E Politi, S Patricia Becerra

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Evaluation of mesenchymal stem cells as anFrontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Germán A MichelisSection of Protein Structure and Function, LRCMB, NEI-NIH, Bethesda, MD, USA.
Luis E PolitiDepartment of Biology, Pharmacy and Biochemistry, Instituto de Investigaciones Bioquímicas (INIBIBB), Universidad Nacional del Sur (UNS)-CONICET, Bahía Blanca, Argentina.
S Patricia BecerraSection of Protein Structure and Function, LRCMB, NEI-NIH, Bethesda, MD, USA. becerras@nei.nih.gov.

Funding

Role of Protein Interactions in Retina Development and FunctionZIAEY000306 · NEI · NATIONAL EYE INSTITUTE · PI BECERRA, S. PATRICIA · 2009 to 2025
$15.6M
Therapeutics for the chorioretinaZIAEY000438 · NEI · NATIONAL EYE INSTITUTE · PI BECERRA, S. PATRICIA · 2009 to 2025
$6.7M
ROLE OF PROTEIN INTERACTIONS IN RETINA DEVELOPMENT AND FUNCTIONZ01EY000306 · NEI · NATIONAL EYE INSTITUTE · PI BECERRA, SOFIA P · 1995 to 2008
$2.3M
Intramural NIH HHS Z01 EY000306Intramural NIH HHS ZIA EY000306
6 · The paper itself

Abstract

Since its inception, primary retinal cultures have been an in vitro tool for modeling the in vivo environment of the retina for biological studies on development and disease. They offer simple and controlled experimental approaches when compared to in vivo models. In this review we highlight the strengths and weaknesses of primary retinal culture models, and the features of dispersed retinal cell cultures.

Indexed as

Cell Culture TechniquesRetinaBiologyCell DifferentiationNeuronsCell linesIn vitro modelsIn vivo modelsOrganoidsPrimary culturesRetina

Identifiers

PMID37440087
PMCPMC13531871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.