ReviewAdvances in experimental medicine and biology2023
Modification of Müller Glial Cell Fate and Proliferation with the Use of Small Molecules.
Review in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 author at 1 institution in 1 country.
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Abstract
In recent years, reprogramming Müller glia by overexpressing Ascl1 and other transcription factors has shown promise for the regeneration of postmitotic retinal neurons, primarily bipolar cells, following injury. Müller glial proliferation and efficiency of neuronal differentiation can be modified by the use of small molecules in various systems. The molecules and pathways studied thus far share remarkable consistency with astrocytes. In this mini review, we provide an overview on the modulation of Müller glial proliferation and cell fate using small molecules in injury and reprogramming. We also compare these observations to what has been observed in astrocytes.
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